Lowe Down
Derek Lowe
January 22, 2009
Perhaps I should clarify who these people are. My career has been in drug discovery, so I've been a customer for everything from 100 milligrams of a competitor compound to a few hundred grams of an intermediate. The orders that have to be dealt with…
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Derek Lowe
June 2, 2008
The pharmaceutical industry, like any large and complicated mechanism, holds itself together with an array of more or less balanced forces. They shift and change over time, finding new equilibria, but there are always factors pushing from both sides.…
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Derek Lowe
April 2, 2008
I've long been sure that there is no one model for successful drug development. My confidence comes from history and statistics. There is, of course, a strong motivation to find a better way to discover and develop drugs, because there's an awful lot…
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Derek Lowe
January 17, 2008
I'm a chemist, so I tend to see the drug discovery world through a chemocentric filter. In my first few years, it was easy for me to believe that medicinal chemists were the key to the whole enterprise. (One good thing about this industry is that the…
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Derek Lowe
May 2, 2007
There's an interesting double bind that sometimes happens in R&D. You can end up in a situation where the changes that most need to be made are in the riskiest place to make them. These are high-wire acts like tweaking a metal alloy used in a crucial…
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Derek Lowe
January 26, 2007
How will low-wage regions affect domestic chemistry services?
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