Catalent Pharma Solutions has licensed a new taste-masking technology developed by the New Jersey Institute of Technology (NJIT). The technology was developed to mask the most challenging, unpleasant and bitter tasting pharmaceutical active ingredients.
Catalent will complete technology transfer to its cGMP facilities to support manufacture of new dosage forms such as its Zydis fast dissolve platform. The taste-masking technology is expected to be effective for developing a wide variety of formulations including granules/sachets, sprinkles, chewables, effervescent and oral dispersible tablets.
“Taste masking of fine drug particles has remained a technical challenge for formulators,” said Dr. Rajesh Davé, Distinguished Professor and Principal Investigator at NJIT. “Through funding from Catalent, we have been able to leverage our expertise to innovate technology and processes that allow for these materials to be cost effectively coated and taste-masked.”
Kurt Nielsen, Ph.D., Catalent’s senior vice president of R&D, said, “Dr. Davé and his group at NJIT are leaders in pharmaceutical particle engineering. The unique approach to API coating is a perfect complement to Catalent’s extensive dose form capabilities and will facilitate formulation of the most difficult-to-taste-mask actives. Catalent has already produced the first feasibility samples, which have exceeded our expectations. This efficient and versatile taste-masking technology will allow development of new dosage forms delivering significant advantages to our customers and benefits to patients and consumers in global markets.”
Catalent Licenses NJIT Taste-Masking Technology
Published October 10, 2012
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