BioStorage Technologies has initiated the INTEGRITY Study, a 24-month study analyzing human whole blood samples to measure the impact on the long-term integrity of DNA and RNA when various preparation methods, storage temperatures and storage times are applied.
The study will be conducted at the company’s global biorepository in Indianapolis, and will compare fresh samples, frozen pre-extracted samples and extracted nucleic acids, which require freeze/ thaw cycles for processing. Storage temperatures and aliquoting strategies will be evaluated and reported during the study.
“The INTEGRITY study has a unique comprehensive study design that will help provide the industry with recommended best practices and techniques to support the optimal preservation of DNA and RNA samples for prospective and retrospective research studies,” said Lori Ball, chief operating officer, BioStorage Technologies. “Our goal is to determine the effects of various preparation methods on whole blood samples for nucleic acid extraction and the optimal length of time and best temperature to store samples for future research.”