Breaking News

SafeBridge Launches Predictive Tox Capabilities

By Kristin Brooks | December 10, 2013

Aims to enable higher throughput and risk prioritization strategies

SafeBridge Consultants, a division of Trinity Consultants, Inc., has launched computational predictive toxicology services to the biopharmaceutical and chemical industry, designed to enable higher throughput and risk prioritization strategies.
SafeBridge is an authorized user of Derek Nexus from Lhasa Ltd., a knowledge-based expert system for the prediction of toxicological hazard, and Leadscope from Leadscope, Inc., a statistical predictive quantitative structure-activity relationships (QSAR) model.
SafeBridge will apply these two software packages to assist companies in meeting the proposed International Conference on Harmonization (ICH) M7 “Assessment and Control of DNA Reactive (Mutagenic) Impurities in Pharmaceuticals to Limit Potential Carcinogenic Risk” guideline; conduct risk assessments of extractable and leachable chemicals into drug products; assess the potential toxicity of contaminants in drugs; and assist in chemical synthetic process development.
blog comments powered by Disqus
  • Elemental Impurity Testing

    Elemental Impurity Testing

    Dr. Andrew Fussell, PANalytical ||January 28, 2016
    Advances in elemental impurity testing aid compliance with new USP requirements

  • Heavy Metals in Drug Products

    Heavy Metals in Drug Products

    Nikki Schopp, Team Leader in charge of ICP-MS, ICP-OES and AA testing, SGS||January 29, 2015
    The potential presence of trace amounts of heavy metals in drug products is a real cause for concern with regulators.

  • Microbiological Testing & Contamination Control

    Microbiological Testing & Contamination Control

    Daniel L. Prince, Ph. D., Christopher J. Waskewich, M.S., Kristah J. Kohan, B.S. and Danina G. Rinaldi, B.S. , Gibraltar Laboratories, Inc.||March 7, 2014
    An opinion on the microbial limit test with reference to harmonization.