Recent developments in cell line engineering have allowed for higher cell densities and productivity rates. In order to achieve their full production potential, these cell lines require nutrient-rich media. However, these feeds can be difficult to dissolve and require complicated time-consuming preparation protocols, according to the company.
BalanCD CHO Feed 4 is designed and formulated to prepare easily using a simplified hydration procedure that does not require pH adjustments. BalanCD CHO Feed 4 maintains pH stability in culture and is designed to support growth while minimizing the production of metabolites that adversely affect titer levels; according to the company, this results in process consistency, significantly higher protein production and protein quality.
“Surveys of large-scale culture media end-users identify time and effort required for mixing powdered media as a top concern. By applying our expertise at media development and formulation we are able to deliver a product that provides performance, flexibility and ease-of-use that facilitates a more robust process.” said Dr. Jessie H.-T. Ni, chief scientific officer of Irvine Scientific. “This new Feed is a significant addition to our BalanCD CHO platform that is designed to streamline the development and scale-up process to help our customers get to market faster.”