Glossary

No Observed Adverse Effect Level (NOAEL)

03.25.13

A dose in toxicology studies that produces no adverse effects.
  • ADME/T

    See Absorption, Distribution, Metabolism and Excretion/ Toxicology.…
    02.27.12

  • Absorption, Distribution, Metabolism and Excretion/Toxicology (ADME/T)

    The objective of ADME/T testing is to measure what happens to a compound in the human physiology. ADME/T tests are done during the preclinical stage of the drug discovery process and are a necessary part of any clinical trial, prior to filing an IND.…
    02.27.12

  • Contract Research Organization (CRO)

    A company involved in performing non-clinical or clinical research on a contract basis for a pharmaceutical or Biotech company, research organization, or other health organization. For non-clinical CROs, studies or full programs are contracted by the…
    02.27.12