05.05.16
Entegris, Inc. has launched its new Aramus 2D bag assembly for single-use bioprocessing applications. Available in 500-ml, 1-liter and 2-liter sizes, Aramus assemblies use ultrapure, advanced film technology that is comprised of one fluoropolymer, gamma-stable film in a single layer. According to the company, the new film provides an increased level of security and protection from particles and eliminates many of the common extractables from traditional single-use bags that can leach into bioprocessing fluids.
“Entegris has a long history of providing advanced, polymer-based technologies for leading-edge processes that have stringent quality standards and contamination controls. This served us well in developing a single, strong bioprocessing film that maintains gamma stability,” said Entegris director of Life Sciences, Eric Isberg. “Our new Aramus bag assembly leverages that history and expertise, and provides a new level of purity and protection for final filling with the flexibility for use in a wide variety of other bioprocessing applications.”
The Aramus bag incorporates a film that consists of a high-grade, gamma-stable and durable fluoropolymer material in one layer. Using a single layer avoids the requirement of adhesives and binders commonly used in the industry to meld multiple film layers together for added protection. These adhesives and binders, along with particulates from the films, can leach into bioprocess materials and result in contamination.
Aramus single-use assemblies are manufactured in an ISO Class 5 cleanroom and offer universal material compatibility and allow for easier validation, according to the company. Moreover, the Entegris fluoropolymer technology offers utility in a wider range of operating temperatures, including increased efficacy in frozen applications (to -85°C) to reduce the risk of assembly breakage.
“Entegris has a long history of providing advanced, polymer-based technologies for leading-edge processes that have stringent quality standards and contamination controls. This served us well in developing a single, strong bioprocessing film that maintains gamma stability,” said Entegris director of Life Sciences, Eric Isberg. “Our new Aramus bag assembly leverages that history and expertise, and provides a new level of purity and protection for final filling with the flexibility for use in a wide variety of other bioprocessing applications.”
The Aramus bag incorporates a film that consists of a high-grade, gamma-stable and durable fluoropolymer material in one layer. Using a single layer avoids the requirement of adhesives and binders commonly used in the industry to meld multiple film layers together for added protection. These adhesives and binders, along with particulates from the films, can leach into bioprocess materials and result in contamination.
Aramus single-use assemblies are manufactured in an ISO Class 5 cleanroom and offer universal material compatibility and allow for easier validation, according to the company. Moreover, the Entegris fluoropolymer technology offers utility in a wider range of operating temperatures, including increased efficacy in frozen applications (to -85°C) to reduce the risk of assembly breakage.