Successfully optimized the different regions:
• Small molecule inhibitor, novel IP generation
• Spacer: length and orientation
• Linker: length
• CRBN ligand
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Literature / Brochures
Targeted Protein Degradation
Syngene has considerable experience solving synthetic chemistry and purification challenges with PROTACS.
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More Literature / Brochures by Syngene
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Brochures
Biologics and Manufacturing
Syngene offers Biologics development and Biomanufacturing solutions in both mammalian and microbial systems.01.15.21
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Chemical Development
Syngene has full value-chain Process Research and Development (PRD) capabilities for NCEs and advanced intermediates.01.14.21
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Clinical Development
Syngene supports early-phase to late-phase clinical trials required for drug development programs across a wide range of therapeutic areas.01.13.21
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Commercial Manufacturing
Syngene supports manufacturing of regulatory starting materials, APIs, HPAPI, NCEs and novel advanced intermediates.01.12.21
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Formulation Development
Syngene supports both development and manufacturing of Drug Products from early to late stage.01.11.21
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ICH Stability Studies
One of the largest Stability facilities in Asia, Syngene supports both small and large molecules from early development to CMC filing and commercialization.01.08.21
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Oligonucleotides
Syngene's services encompass Therapeutic oligonucleotides, Diagnostic Oligonucleotides, Enzymatic synthesis and analytical services.01.07.21
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Your Pre-clinical Toxicology Program Needs a Strategy
At Syngene, we have developed a roadmap across pre-IND, IND and NDA that seamlessly integrate the various pre-clinical studies.Case Studies Released on 01.14.2021
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The Dedicated Center
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The Many Benefits of Outsourcing Stability: A Baxter-Syngene Case study
Learn why Baxter chose to partner with Syngene for Stability studies, the business flow, governance mechanism and metrics that were implemented.Case Studies Released on 01.07.2021
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Syngene and Deerfield Discovery and Development (3DC) sign 5-year strategic collaboration
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