Pre-formulation and Formulation Services

• Raw material sourcing
• Solubility profile (in buffers and non-aqueous solvents) and partition coefficient of API
• API compatibility with excipients
• Stability of API and factors affecting stability (including heat, light and pH)
• Method development and method transfer for particle size of wet and dry particles by laser diffraction (for both API and the formulation)
• API characterization by DSC, powder X-ray diffraction, FTIR and particle morphology by optical microscopy
• Formulation and packaging compatibility
• Surface tension of aqueous and non-aqueous liquids

Formulation Services

• Particle size (dry, wet and sprays)
• Rheology/viscosity
• pH
• Specific gravity
• Informal stability/formulation stress testing (both physical and chemical)
• Antimicrobial Effectiveness Testing (AET)
• Formulation container closure compatibility assessment