For our Top Companies issue, we asked Ronald A. Rader, president of the Biotechnology Information Institute, to provide a list of the Top 50 Biopharma Products by 2010 revenues (in millions). Mr. Rader subscribes to the same criteria as Contract Pharma — that iopharmaceuticals are pharmaceuticals manufactured by living organisms (involving biotechnology/bioprocessing), including recombinant and non-recombinant proteins, antibodies and vaccines. Thus, “If it’s small molecule, it ain't biopharma!”
—GYR
About the Author
Ronald A. Rader is a consultant and the author and publisher of BIOPHARMA: Biopharmaceutical Products in the U.S. and European Markets (www.biopharma.com), the only information resource/reference specializing in biopharmaceuticals. The Biotechnology Information Institute is located in Rockville, MD. Mr. Rader may be contacted at biotech@biopharma.com.
|
Trade Name |
Description |
Marketer |
2010 Revenues |
|
1. Enbrel |
TNF Mab, rDNA |
Amgen / Pfizer |
$7,287 |
|
2. Avastin |
VEGF Mab, rDNA |
Roche |
$6,973 |
|
3. Rituxan |
CD20 Mab, rDNA |
Roche / Biogen |
$6,859 |
|
4. Remicade |
TNF Mab, rDNA Mab, rDNA |
Johnson & Johnson | $6,520 |
|
5. Herceptin |
HER2 receptor |
Roche |
$5,859 |
|
6. Humira |
TNF Mab, rDNA |
Abbott |
$5,488 |
|
7. Lantus |
Insulin glargine, rDNA |
Sanofi |
$4,834 |
|
8. Neulasta |
G-CSF, rDNA, PEG |
Amgen |
$3,558 |
|
9. Lucentis |
VEGF Mab Fab, rDNA |
Roche |
$3,106 |
|
10. Aranesp |
EPO, darbo-, rDNA |
Amgen |
$2,995 |
|
11. Avonex |
Interferon beta-1a, rDNA |
Biogen Idec |
$2,518 |
|
12. Prevnar-7 |
Pneumococcal Vaccine(7)-CRM197 |
Pfizer | $2,400 |
|
13. Rebif |
Interferon beta-1a, rDNA |
Merck |
$2,297 |
|
14. NovoLog |
Insulin aspart, rDNA |
Novo Nordisk |
$2,198 |
|
15. Novolin |
Insulin, rDNA |
Novo Nordisk |
$2,185 |
|
16. Advate |
Factor VIII, rDNA |
Baxter |
$2,095 |
|
17. Humalog |
Insulin lispro, rDNA |
Lilly |
$2,054 |
|
18. Procrit / Eprex |
EPO, rDNA |
Johnson & Johnson |
$1,900 |
|
19. Erbitux |
EGF receptor Mab, rDNA |
Bristol-Myers Squibb |
$1,791 |
|
20. Pegasys |
Interferon alfa, rDNA, PEG |
Roche |
$1,775 |
|
21. Betaseron |
Interferon betaser, rDNA |
Bayer |
$1,661 |
|
22. NovoSeven |
Factor VIIa, rDNA |
Novo Nordisk |
$1,483 |
|
23. BOTOX |
Botulinum Toxin A |
Allegan |
$1,414 |
|
24. NeoRecormon |
EPO, rDNA |
Roche |
$1,387 |
|
25. Kogenate |
FS Factor VIII, rDNA |
Bayer |
$1,383 |
|
26. Neupogen |
G-CSF, rDNA |
Amgen |
$1,286 |
|
27. Levemir |
Insulin detemir, rDNA |
Novo Nordisk |
$1,271 |
|
28. Engerix-B |
Hepatitis B Vaccine, rDNA |
GlaxoSmithKline |
$1,200 |
|
29. Tysabri |
Integrin Mab, rDNA |
Biogen Idec / Elan |
$1,089 |
|
30. Humulin |
Insulin, rDNA |
Lilly |
$1,089 |
|
31. Synagis |
RSV Mab, rDNA |
MedImmune/AstraZeneca |
$1,038 |
|
32. Gardasil |
HPV vaccine, rDNA |
Merck |
$998 |
|
33. Varivax |
Varicella Vaccine |
Merck |
$929 |
|
34. Norditropin |
Somatropin, rDNA |
Novo Nordisk |
$887 |
|
35. Genotropin |
Somatropin, rDNA |
Pfizer |
$885 |
|
36. Forteo |
Parathyroid hormone, rDNA |
Lilly |
$830 |
|
37. PEG-Intron |
Interferon alfa-2b, rDNA |
Merck |
$737 |
|
38. Orencia |
CTLA4-Ig, rDNA |
Bristol-Myers Squibb |
$733 |
|
39. Cerezyme |
Glucocerebrosidase, rDNA |
Genzyme/Sanofi |
$720 |
|
40. Xolair |
mmunoglobulin E Mab, rDNA |
Roche & Novartis | $692 |
|
41. Gonal-f |
FSH rDNA |
Merck Serono |
$674 |
|
42. BeneFIX |
Factor IX, rDNA |
Pfizer |
$643 |
|
43. Menactra |
Meningococcal Vaccine |
Sanofi |
$626 |
|
44. Pulmozyme |
DNase, rDNA |
Roche |
$554 |
|
45. Soliris |
Complement C5 Mab, rDNA |
Alexion | $541 |
|
46. Follistim AQ |
FSH rDNA |
Merck Serono |
$528 |
|
47. Nutropin |
Somatropin, rDNA |
Roche |
$504 |
|
48. TNKase |
tPA, TNK-, rDNA |
Roche |
$496 |
|
49. Helixate FS |
Factor VIII, rDNA |
Bayer |
$480 |
|
50. Actemra |
IL-6 receptor mAb, rDNA |
Roche |
$428 |
