• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Manufacturing
    • Packaging
    • Development
    • Compliance
    • Top 25
    • Directory
    • Microsites
    • Events
    • More
  • Magazine
  • News
  • Manufacturing
  • Packaging
  • Development
  • Compliance
  • Top 25
  • Directory
  • Microsites
  • Events
  • Current / Back Issue
    Features
    Editorial
    Columns
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Subscribe Now
    Advertise Now
    Top Features
    Hygienic Packaging Technology

    Trends in Solid Oral Dosage Delivery

    5 Reasons Paper Has No Place in Contract Manufacturing

    Injectable Drug Delivery Trends

    Pharmaceutical Manufacturing Equipment Trends
    Breaking News
    Online Exclusives
    Industry News
    Collaborations & Alliances
    Promotions & Moves
    Trials & Filings
    Financial Reports
    Bio News & Views
    Custom Sourcing News
    Packaging & Tracking
    CRO News
    Live From Shows
    Top News
    Innoforce and dMed Enter Development Collaboration

    Matica Biotechnology Breaks Ground on Cell and Gene Therapy Site

    Four Female Leaders Appointed to Cell & Gene CDMO

    Fusion Pharmaceuticals Acquires IPN-1087

    Strata Oncology Unveils Strata PATH Trial
    APIs
    Aseptic Processing
    Cleaning Validation
    Clinical Trial Materials
    Cytotoxics and High Potency Manufacturing
    Equipment
    Excipients
    Extractables and Leachables
    Facilities
    Fill/Finish
    Lyophilization
    Parenterals
    Process Development
    Process Validation
    Risk Management
    Scale-up/ Technology Transfer
    Solid Dosage/ Creams/ Ointments

    Matica Biotechnology Breaks Ground on Cell and Gene Therapy Site

    WuXi AppTec Completes OXGENE Acquisition

    Trends in Solid Oral Dosage Delivery

    Injectable Drug Delivery Trends

    Oral Solids: Market & Technology Trends
    Capsules
    Cold Chain Management
    Injectables
    Logistics
    Serialization
    Solid Dosage / Semi-solids
    Supply Chain
    Vials

    Hygienic Packaging Technology

    Reshaping the Pharmaceutical Supply Chain

    Serialization: Level 5 Solution

    Covectra Introduces Next-Gen Serialization Solution

    Bormioli Opens New Glass Research Center
    Analytical Services
    Bioanalytical Services
    Bioassay Developement
    Biologics, Proteins, Vaccines
    Biosimilars
    Chemistry
    Clinical Trials
    Drug Delivery
    Drug Development
    Drug Discovery
    Formulation Development
    Information Technology
    Laboratory Testing
    Methods Development
    Microbiology
    Preclinical Outsourcing
    R&D
    Toxicology

    Innoforce and dMed Enter Development Collaboration

    Matica Biotechnology Breaks Ground on Cell and Gene Therapy Site

    Four Female Leaders Appointed to Cell & Gene CDMO

    Strata Oncology Unveils Strata PATH Trial

    Alimentiv Acquires McDougall Scientific
    Filtration & Purification
    GMPs/GCPs
    Inspections
    QA/QC
    Regulatory Affairs
    Validation

    Guide to Maintaining Validation of Older Facilities: Why, When and How

    The Year of COVID: How FDA Coped with a Worldwide Pandemic in 2020 and What to Expect in 2021

    Top BioPharma Form Accumulus Synergy

    Global Biosciences Co. Selects ValGenesis VLMS

    Gene Therapy Co. Selects ValGenesis' SaaS Platform
    Companies
    Categories
    Corporate Capabilities
    Add New Company
    Contract Service Directory Companies
    Baxter BioPharma Solutions

    Reed-Lane

    Syngene

    Aphena Pharma Solutions

    Alcami
    Companies
    News Releases
    Posters
    Brochures
    Services
    Videos
    Case Study
    White Papers
    Jobs
    Contract Service Directory Companies
    Reed-Lane

    Aphena Pharma Solutions

    PCI Pharma Services

    Emergent BioSolutions

    Federal Equipment Company
    Webinars
    Live From Shows
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
      • Enewsletter Archive
      • Digital Edition
    • Directory
      • Companies
      • Categories
      • Corporate Capabilities
      • Add Your Company
    • Manufacturing
      • APIs
      • Aseptic Processing
      • Cleaning Validation
      • Clinical Trial Materials
      • Cytotoxics and High Potency Manufacturing
      • Equipment
      • Excipients
      • Extractables and Leachables
      • Facilities
      • Fill/Finish
      • Lyophilization
      • Parenterals
      • Process Development
      • Process Validation
      • Risk Management
      • Scale-up/ Technology Transfer
      • Solid Dosage/ Creams/ Ointments
      • cGMP Manufacture
    • Packaging
      • Capsules
      • Cold Chain Management
      • Injectables
      • Logistics
      • Serialization
      • Solid Dosage / Semi-solids
      • Supply Chain
      • Vials
    • Development
      • Analytical Services
      • Bioanalytical Services
      • Bioassay Developement
      • Biologics, Proteins, Vaccines
      • Biosimilars
      • Chemistry
      • Clinical Trials
      • Drug Delivery
      • Drug Development
      • Drug Discovery
      • Formulation Development
      • Information Technology
      • Laboratory Testing
      • Methods Development
      • Microbiology
      • Preclinical Outsourcing
      • R&D
      • Toxicology
    • Compliance
      • Filtration & Purification
      • GMPs/GCPs
      • Inspections
      • QA/QC
      • Regulatory Affairs
      • Validation
    • Top 25 Pharma & BioPharma
    • Contract Pharma Direct
    • Breaking News
    • Online Exclusives
    • Slideshows
    • Experts Opinions
    • Surveys
      • Outsourcing Survey
      • Salary Survey
    • Glossary
    • Videos
    • Podcasts
    • White Papers
    • Infographics
    • Contract Pharma Conference
      • Contract Pharma Conference
      • Speakers
      • Exhibitors
      • Conference Sessions
    • Supplier Microsite
      • Companies
      • News Releases
      • Posters
      • Brochures
      • Services
      • Videos
      • Case Study
      • White Papers
    • eBook
    • Webinars
    • Events
      • Industry Events
      • Live from Show Events
      • Webinars
    • Classifieds / Job Bank
      • Classifieds
      • Job Bank
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Features

    Extended Content Labels

    The simple yet complicated solution for pharma’s ever-expanding printed content needs

    Extended Content Labels
    Related CONTENT
    • Schreiner MediPharm Joins DoseID Consortium
    • Reed-Lane Adds Second Track & Trace Cartoning Line
    • Preparing to Adopt Intelligent Label Management
    • Legacy Pharmaceutical Packaging Adds Facility for 3PL Ops
    • TurboFil Introduces Syringe Filling & Assembly System
    Tom Spina, President & CEO, Luminer06.04.20
    In 2018 the global pharmaceutical labeling market reached $4.7 billion. That represents a decade of steady year over year gains, with an additional 5.5% growth expected by 2024.

    Among the reasons for this surge is an increasing demand for pharmaceutical products overall, which in turn is at least partially attributed to a growing geriatric population. That’s easy math: more people needing more medicine means more labels. However, an aging population might be the only simplistic factor in pharma labeling’s consistent uptick.

    Simply put, it’s complicated. While the worldwide supply chain gets more interconnected, expansive and diverse, novel and highly sophisticated formulations stream through the approval pipeline, onto the production floor and into the market. Meanwhile, regulations continue to be adopted, adapted and strengthened across a wide variety of regions, often in disparate, inconsistent fashions. New markets, new drugs and new rules combine to make the manufacturing and packaging processes exponentially more intricate, as the amount of information a medicine must communicate to pharmacists and end users expands despite limited packaging print space.

    Considering this, it’s no wonder that one of the niches helping to drive pharma labeling’s global growth is a solution that addresses each of these issues with room to spare: Extended Content Labels (ECLs).

    ECL 101
    First, let’s define the parameters. Utilized in various facets of pharmaceutical packaging, extended content labels can range from as a few as two pages (think of “peel and reseal” labels commonly found on many OTC products) to full-fledged booklets of up to 60 pages, which are more typically used for clinical trials and prescription drug packaging. Their overarching benefit is space consolidation: ECLs allow for more information to be placed on a label where a package cannot support all preferred or necessary content on a simple, single-ply label.

    With ECLs, you can do a lot with a little, as flipbook and fold-out styles allow print space to be multiplied several times over while taking up little more total space than the surface of an ordinary label. The result is ample room for a lengthy list of mounting mandatory information, including:
    • Warnings and directives that comply with regulatory guidelines, not only in one country but often across multiple nations or trade regions, as the number of international customers on the ledgers of pharma companies, CMOs and contract packagers continues to climb.
    • Serialization and traceability requirements, again with the mindset that different countries across the same manufacturer’s customer base may have differing mandates.
    • Different languages. This accounts not only for international customers but also domestic ones. For example, Canada needs labels in English and French, while in the United States Spanish is quickly becoming an unofficial second national language.
    • Specific, detailed instructions. More and more prescription pharmaceuticals require strict adherence regimens, which in turn necessitate detailed printed instructions for doctors, pharmacists and end users. Relatedly, clinical trials often need tight control, another condition that lends itself to more labeling content rather than less.
    Overlapping this necessity for more printed information is a seemingly contradictory desire – and in some places, like Europe, even strongly recommended guidelines – for smaller, more environmentally friendly packaging. From a spatial standpoint, without ECLs this conundrum can be virtually impossible to square with reality; the math simply doesn’t add up.  From a sustainability standpoint, labels can generally be composed of more eco-conscious (and cost-effective) materials than, for example, plastic bottles.

    Advanced ECL
    So ECLs are just a straightforward, logical means of providing more content space for pharma products. Simple, right?

    Not so fast. Much like the pharma landscape at large, issues surrounding ECLs can also be quite complex, with decisions that impact a product’s journey along the supply chain and effectiveness upon its final destination, the end user.

    One of the challenges is inspection. It must be remembered that, with ECLs, at some point in the process pages will inevitably be covered, rendering the print unreadable until the label is opened by the customer. Because this printed information is often critical to FDA compliance, systems must be implemented that allow inspection to take place at various points in the production cycle.
    Pharmaceutical production requires 100% inspection whether you are producing a one-page label or a 60-page label.

    At Luminer, among the most complicated ECL applications we encounter is when a client needs to place a large number of pages around a small diameter vial. This is akin to wrapping a small book around a curved surface – try it, it’s not easy. Even if the paper used is exceedingly flexible, when the booklet is wrapped pages on top become shorter than pages on the bottom. This discrepancy requires systems designed to cut each page properly to get the correct wrap of the label on the container. As bottles get ever-smaller and pages ever-greater, we’ve had to continually develop new cutting, folding, and gluing technologies to yield a perfect ECL fit.

    Certain aerosol applications also can be tricky, especially with requests for both the ECL instructional label and the front prime label to be on the same base, so that the entire product can be labeled in one pass.  We accomplish this by combining up to ten print heads and incorporating state-of-the-art reregistering capability – a process that allows us to place a folded preprinted book on a prime label in such a way that the pages will also fall into place as the label is wrapped on the aerosol can. This helps assure optimal aesthetic appeal on store shelves. 

    Extended content labels are a solution to a conundrum. Even in an eco-conscious, message-cluttered landscape where less is more, in reality pharma companies know that more is more. They need more space for more information supplementing more products in more and more disparate end user regions. And as simple as “creating more space” sounds, the logistics can cause something they need less of: headaches.

    To counteract this, pharma label manufacturers will need to step up and solve ECL issues before they start, using innovation to relieve medicine makers and contract packagers of the sort of simple yet complicated problems that arrive when more space is needed on a finite package. 


    Tom Spina is president and chief executive officer of Luminer, which specializes in combining adhesive coating technology with narrow web flexographic printing and converting expertise. The company serves several industry niches, chief among them extended content labels (ECLs) for clinical trial and other pharmaceutical applications. Located in Lakewood, NJ and Red Lion, PA, Luminer’s two facilities are each ISO 9001:2015 certified, operate under cGMP guidelines, and regularly undergo audits from high-profile pharmaceutical, cosmetics and health & beauty aid clients.
    Suggested For You
    Schreiner MediPharm Joins DoseID Consortium Schreiner MediPharm Joins DoseID Consortium
    Reed-Lane Adds Second Track & Trace Cartoning Line Reed-Lane Adds Second Track & Trace Cartoning Line
    Preparing to Adopt Intelligent Label Management Preparing to Adopt Intelligent Label Management
    Legacy Pharmaceutical Packaging Adds Facility for 3PL Ops Legacy Pharmaceutical Packaging Adds Facility for 3PL Ops
    TurboFil Introduces Syringe Filling & Assembly System TurboFil Introduces Syringe Filling & Assembly System
    LaunchWorks CDMO Approved to Provide Viral Transport Media LaunchWorks CDMO Approved to Provide Viral Transport Media
    LaunchWorks CDMO Approved for Viral Transport Media LaunchWorks CDMO Approved for Viral Transport Media
    The Pandemic’s Become an Insurmountable Opportunity The Pandemic’s Become an Insurmountable Opportunity
    Fresenius Kabi Introduces RFID Smart Labels for Essential Meds Fresenius Kabi Introduces RFID Smart Labels for Essential Meds
    Lewis Press Lewis Press
    Cut Sheet Labels Cut Sheet Labels

    Related Features

    • Solid Dosage/Semi-solids
      Hygienic Packaging Technology

      Hygienic Packaging Technology

      Growing consumer demand for health products highlights hygienic packaging.
      John Brown, Vice President of Global Marketing, Selig 03.01.21

    • Drug Delivery | Solid Dosage/Creams/Ointments
      Trends in Solid Oral Dosage Delivery

      Trends in Solid Oral Dosage Delivery

      Capsule demand continues to rise due to this delivery system’s versatility.
      Anita Solanki, Milind Biyani and Jnanadeva Bhat, PhD , ACG Capsules 03.01.21

    • Information Technology
      5 Reasons Paper Has No Place in Contract Manufacturing

      5 Reasons Paper Has No Place in Contract Manufacturing

      Digital solutions create more efficient manufacturing processes and eliminate delays.
      Dave Edwards, Chief Revenue Officer, MasterControl 03.01.21


    • Drug Delivery | Parenterals
      Injectable Drug Delivery Trends

      Injectable Drug Delivery Trends

      How medication trends are driving the shift to patient-friendly drug delivery systems.
      Peter Soelkner, Managing Director, Vetter 03.01.21

    • Pharmaceutical Manufacturing  Equipment Trends

      Pharmaceutical Manufacturing Equipment Trends

      Demand for flexibility remains the driving force behind equipment systems.
      Kristin Brooks, Managing Editor, Contract Pharma 03.01.21

    • Drug Delivery | Solid Dosage/Creams/Ointments
      Oral Solids:   Market & Technology Trends

      Oral Solids: Market & Technology Trends

      Oral solids remain the preferred route of drug delivery due to their cost-effectiveness, ease of manufacturing, and patient-friendly dose form options.
      Tim Wright, Editor, Contract Pharma 03.01.21


    • Nutraceutical Manufacturing:  Meeting the Challenges of Today, Planning for  Tomorrow

      Nutraceutical Manufacturing: Meeting the Challenges of Today, Planning for Tomorrow

      Companies continue balancing high demand, supply disruption, and worker safety during the pandemic.
      Sean Moloughney, Editor, Nutraceuticals World 03.01.21

    • 2021 Contract  Manufacturing Survey

      2021 Contract Manufacturing Survey

      Our fourth annual audience poll indicates continued reliance on manufacturing partners, particularly for small businesses.
      Sean Moloughney, Editor, Nutraceuticals World 03.01.21

    • APIs
      Small Molecule Development Trends

      Small Molecule Development Trends

      A Q&A with Cambrex Edinburgh’s site director, Mark Benger.
      Tim Wright, Editor, Contract Pharma 03.01.21


    • APIs | Cytotoxics and High Potency Manufacturing
      Challenges & Opportunities Facing Small & Emerging Biopharma Companies

      Challenges & Opportunities Facing Small & Emerging Biopharma Companies

      A Q&A with Christian Dowdeswell, vice president and head of commercial development for small molecules at Lonza.
      Tim Wright, Editor, Contract Pharma 03.01.21

    • Drug Delivery | Solid Dosage/Creams/Ointments
      Medicated Chewing Gum: A Modern Oral Drug Delivery System

      Medicated Chewing Gum: A Modern Oral Drug Delivery System

      Development and manufacture of medicated chewing gum continues to gain momentum.
      Rukayat Adedeji, Contributing Writer 03.01.21

    • APIs
      Small Molecule API CDMO: A Capital Intensive Business?

      Small Molecule API CDMO: A Capital Intensive Business?

      Exploring small molecule API market trends.
      Dr. Michele Jermini and Dr. Enrico Polastro, Contributing Writers 03.01.21


    • Serialization
      Serialization: Level 5 Solution

      Serialization: Level 5 Solution

      Why a Level 5 solution is required for small pharma companies to fully harness serialization investment.
      Steve Wood, President & CEO, Covectra 03.01.21

    • Solid Dosage/Creams/Ointments
      High Drug Loading Amorphous Solid Dispersions

      High Drug Loading Amorphous Solid Dispersions

      A Novel Tablet Architecture for Amorphous Solid Dispersions to Achieve High Drug Loadings
      Deanna Mudie and Aaron Stewart, Lonza 01.27.21

    • Parenterals
      Parenteral Drug Delivery Trends

      Parenteral Drug Delivery Trends

      A Q&A with Lubrizol Life Science Health’s CDMO Division President, Rob Lee.
      Kristin Brooks, Managing Editor, Contract Pharma 01.27.21

    Trending
    • BMS Expands Cell Therapy Manufacturing Capabilities
    • AbbVie Opts To Acquire Mitokinin
    • Bormioli Opens New Glass Research Center
    • WuXi AppTec Completes OXGENE Acquisition
    • Arcline Investment Acquires ChargePoint Technology
    Breaking News
    • Innoforce and dMed Enter Development Collaboration
    • Matica Biotechnology Breaks Ground on Cell and Gene Therapy Site
    • Four Female Leaders Appointed to Cell & Gene CDMO
    • Fusion Pharmaceuticals Acquires IPN-1087
    • Strata Oncology Unveils Strata PATH Trial
    View Breaking News >
    CURRENT ISSUE

    March 2021

    • Hygienic Packaging Technology
    • Trends in Solid Oral Dosage Delivery
    • 5 Reasons Paper Has No Place in Contract Manufacturing
    • Injectable Drug Delivery Trends
    • Pharmaceutical Manufacturing Equipment Trends
    • Oral Solids: Market & Technology Trends
    • Nutraceutical Manufacturing: Meeting the Challenges of Today, Planning for Tomorrow
    • 2021 Contract Manufacturing Survey
    • Small Molecule Development Trends
    • Challenges & Opportunities Facing Small & Emerging Biopharma Companies
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Gadot Biochemical Launches New Magnesium Ingredients
    Low Levels of Vitamin D and Calcium Linked to COVID-19 Severity
    Probiotic Evidenced to Assist Digestive Recovery from a Complex Surgery
    Coatings World

    Latest Breaking News From Coatings World

    Chromaflo Technologies Adds Benjamin Woeste as Territory Sales Manager
    Matt Fogel Named Mule-Hide's Territory Manager – Southern Virginia
    Benjamin Moore Launches COMMAND
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Philips, Disney Join Forces to Reduce Childrens' MRI Anxiety
    Philips, Disney Partner to Improve MRI Experience for Children
    FDA OKs Asensus' Senhance for General Surgery
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Innoforce and dMed Enter Development Collaboration
    Matica Biotechnology Breaks Ground on Cell and Gene Therapy Site
    Four Female Leaders Appointed to Cell & Gene CDMO
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    P&G Makes Progress Toward Packaging Circularity in Europe
    Coty Partners with LanzaTech to Introduce Sustainable Ethanol
    Remembering Fred Segal, a Trendsetting Retail Pioneer
    Happi

    Latest Breaking News From Happi

    Coty Partners with LanzaTech to Reduce Its Environmental Impact
    Waterless Beauty, Simplified Routines Shape Clean Beauty at Whole Foods
    Redken Updates Packaging, Adds New Products
    Ink World

    Latest Breaking News From Ink World

    Massilly North America Adds Koenig & Bauer MetalStar 3 Metal Decorating Press
    Hydrocarbon Solvents Market to Surpass $8.1 Billion by 2030
    Access Direct Mail Doubles Revenue with SCREEN's Truepress Jet520HD
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Ashland announces PSA price hike in North America
    Arrow Systems and Sihl form flexible packaging partnership
    Flint Group Packaging announces global price increase
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Joa Announces Expandable Absorbent Core Wrap Solution
    Principle Business Enterprises Celebrates 60 Years
    Mann+Hummel Invests in Pamlico Air
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Spinal Elements Relaunches the Luna XD and Orbit Systems
    Coronavirus Triggers Double-Digit Revenue Dropoff at Smith+Nephew
    FDA Approves Accufix Surgical's Accu-Joint Hemi Implant
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Comercial Kywi Improves Customer Service, Front-Store Operations with Zebra Mobile Solution
    Global Printed Circuit Board Market Projected to Reach $69.32 Billion by 2027
    Global Smart Glass Market to Register 6.8% CAGR Between 2021-28: Grand View Research

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login