Posters
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Pharmaceutical Development for ADCs
Download the ADCs Poster.Released by: Baxter BioPharma Solutions
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Enhanced Delivery Options for Injectables
Download the Enhanced Delivery Options Poster.Released by: Baxter BioPharma Solutions
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BIOSIMILARS: Global Terminology, Strategy & Pathways
Download the Global Terminology, Strategy & Pathways PosterReleased by: Baxter BioPharma Solutions
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Shoot for Share: From Vial to Prefilled Syringe
Download the Shoot for Share Poster.Released by: Baxter BioPharma Solutions
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Regulating Dissolved Oxygen Levels in Culture Media
Download the HypoxyCOOL™ PosterReleased by: Baker
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Clean Air and Containment Decision Map
A risk assessment for the laboratory space should be prepared by, for example, the institution’s Biological Safety Officer.Released by: Baker
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Rapid and effective modulation of dissolved oxygen levels in cell culture media for improved hypoxia
Research from Keele UniversityReleased by: Baker
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How to Better Mimic Cell Physiology
Baker Science Director Kara Held presented at the Inaugural Physiological Oxygen Workshop and Educational Initiative
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Drug Delivery
Novel Drug Delivery Approach to Achieve Zero-order Release Kinetics: Coated Matrix Based Formulation
The objective of this study was to achieve the drug release rate which is independent of time and the concentration from a solid oral tablet dosage form. A zero order, pH independent release formulation for a freely water soluble model drug (Buspiron…Released by: Patheon
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APIs | Excipients
A Novel Technique for Compressing Powder Blends Containing Low Melting Substances and Waxy Materials
The objective of this study was to evaluate a novel technique for compressing blends at low temperatures using Vortex Coolers. Processing of low melting APIs or excipients such as solubilizers/bioavailability enhancers into a tablet dosage form has b…Released by: Patheon
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Development of Oral Fast Disintegrating Tablets Using Direct Compression and Extreme Vertices Method
The purpose of this study was to evaluate the development of oral fast disintegrating tablets by conventional direct compression method and statistical design of experiment. Better results were obtained with lower strength than higher strength tablet…Released by: Patheon
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Comparative Study of Manual Dissolution with On-line UV and Fiber Optical Probe Automated Dissolutio
The purpose of this study was to compare the reliability and reproducibility of manual and automated dissolution-UV methods. Extended-release acetaminophen was selected as the model. This study demonstrated that the fiber optic probe system was prefe…Released by: Patheon
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Effect of Granulation Factors on the Compression Behaviour of a Slow Release Polymeric Matrix Formul
The purpose of this study was to investigate the effect of wet granulation factors on the compression behaviour and other physical characteristics of a slow release polymeric matrix formulation. The water quantity used for granulation was the most im…Released by: Patheon
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Small Scale Optimization of an Active Formulation Roller Compaction Process Using a True Placebo Des
The purpose of this study was to evaluate the use of a true placebo DoE to create a platform process in which to define a viable active formulation process on a roller compactor. The use of placebo DoE was effective in creating a platform process for…Released by: Patheon
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LIBS (Laser Induced Breakdown Spectroscopy) as an At-line Monitor of API Coating Uniformity in a Fil
The purpose of this work was to study the use of LIBS (Laser Induced Breakdown Spectroscopy) as an in-process monitor for uniformity during an API tablet coating process. In-process measurements were taken up to the coating endpoint, and evaluated to…Released by: Patheon
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Capsules
Enteric Coating of Empty HPMC Capsule Shells Using a Wurster Fluid-Bed Coating Process - 2009
The purpose of this study was to develop and optimize a Wurster fluid-bed coating process for applying an enteric coating onto empty hypromellose capsule caps and bodies to achieve acid resistance after filling. Coated capsules were manually filled a…Released by: Patheon
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Optimization of Throughput Conditions for Scale-up of a Roller Compacted Product - 2009
The purpose of this study was to establish the design space and operational conditions for the roller compaction process of a placebo formulation that closely represents a low-dose active formulation. The ribbon density, tensile strength, mean granul…Released by: Patheon
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Optimization of Fast Disintegrating Direct Compression Tablets by Statistical Design - 2009
The purpose of this study is to further optimize and assess the effect of refining magnesium stearate lubricant, sweetener, hardness and thickness levels on the design of a fast disintegrating formulation by direct compression.…Released by: Patheon
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Investigation of Areas of Discoloration on Stability Samples of Pharmaceutical Tablets – A Case Stud
The purpose of this study was to investigate the root cause and potential mechanism behind the areas of discoloration on stability samples of pharmaceutical tablets. The most likely mechanism of tablet discoloration was related to a dehydration react…Released by: Patheon
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Influence of Smooth Roll Surface on Compaction Behavior of Model Formulations - 2010
The purpose of this study was to understand the roller compaction behavior of different model placebo formulations using smooth rolls and to compare their performance against different roll surfaces. This study clearly demonstrates the differences in…Released by: Patheon
