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Aims to increase accessibility to cryoelectron microscopy technology for the global pharmaceutical and biotechnology community.
September 2, 2020
By: Contract Pharma
Contract Pharma Staff
NanoImaging Services, Inc. (NIS), specialists in transmission electron microscopy (TEM), has partnered with Thermo Fisher Scientific to increase accessibility to cryoelectron microscopy (cryoEM) technology for the global pharmaceutical and biotechnology community. NIS’ cryoEM is used in drug discovery and vaccine development applications.
Through its partnership with Thermo Fisher, NIS supporting pharma and biopharma with start-up packages for cryoEM technology, all the way through to completion of projects. NIS is the first contract research organization (CRO) to have established the necessary hardware and software base for full structure enablement from sample to final map production. To date, the company’s facilities, combined with IT infrastructure have supported more than 200 cryoEM projects resulting in more than 60 unique protein structures.
CryoEM has been established as a powerful method for high resolution 3D protein structure determination, succeeding where traditional X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy techniques fail. Pharmaceutical companies can benefit from cryoEM for the analysis and characterization of small amounts of material, large biomolecular complexes or materials that are hard to crystallize.
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