As much as half of all research funding in life sciences is used to repeat experiments, showing that lack of reproducibility in research is an ongoing challenge in the biopharmaceutical industry. A major cause of irreproducibility has been incorrect execution in liquid handling workflows. This collaboration between Andrew Alliance and Sartorius reflects both companies’ strategic investment in designing innovative pipetting solutions to improve reproducibility and simplify the complex and time-consuming workflows.

 

The Andrew Alliance Pipette+ system comprises several components that communicate with one another: electronic single and multichannel pipettes, an intelligent stand, and novel cloud-based software. Andrew Alliance co-developed the Pipette+ system with Sartorius, who is manufacturing the pipette hardware. The hardware is based on Sartorius’s Picus range of award-winning, ergonomic electronic pipettes. Using current-day Internet of Things (IoT) solutions, the pipettes communicate wirelessly with the stand by Bluetooth, and the computerized charging stand communicates with Cloud servers by either Wi-Fi or Ethernet. The pipette transmits data to the stand, such as possible errors, operator identity, and step-by-step actions taken by the operator, ensuring full traceability and improved repeatability.

 

The software system uses Andrew Alliance’s free, browser-based intelligent software environment, OneLab. This software allows intuitive protocol design and simplified protocol execution. For instance, the software can indicate which pipette is to be used at each step in an experiment, preset the required pipetting parameters, and eject tips at the appropriate time. 

 

“We worked together with Andrew Alliance to provide the scientific community with a next-generation solution for manual pipetting. We’ve been at the forefront of the electronic pipette  revolution with our Picus pipette and are now connecting the world of pipetting to the world of computing. This represents a quantitative leap in the performance of electronic pipettes over that of mechanical devices,” said Venkat Rao, head Business Management, EMEA Life Science Research at Sartorius.

 

“Life science researchers should be confident that their often highly limited biological samples, costly reagents and time, are focused on progressing valuable research rather than unnecessarily repeating experiments,” said Piero Zucchelli, chief executive officer and co-founder of Andrew Alliance. “Andrew Alliance and Sartorius, the market leader in electronic pipettes, are addressing the manual liquid handling repeatability problem head on.”