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Koenig has extensive experience in both neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer’s disease.
June 16, 2026
By: Patrick Lavery
Content Marketing Editor
Why This Matters: See our coverage of other industry executive team appointments and promotions here.
Syremis Therapeutics, a clinical-stage biopharmaceutical company developing novel medicines for mental health disorders, appointed Aaron Koenig, MD, Chief Medical Officer.
Koenig, a psychiatrist by trade, is recognized as a drug development leader whose experience includes neuropsychiatric disorders and neurodegenerative diseases. Namely and notably, this area of expertise encompasses Alzheimer’s disease.
Prior to his appointment at Syremis, Koenig held the same Chief Medical Officer post at Syndeio Biosciences and Delix Therapeutics. At Delix, he oversaw development of a range of novel neuropsychiatric drug candidates, according to information provided by Syremis.
Previously, Koenig led multiple neuropsychiatry programs at Sage Therapeutics, where he had held numerous leadership roles. Among the programs Koenig oversaw at Sage were candidates for treatment of cognitive impairment associated with neurodegenerative disease.
Earlier in his career, Koenig worked as a clinical investigator for the Massachusetts Alzheimer’s Disease Research Center.
“I am excited to join Syremis at such a pivotal time,” Koenig said. “I know firsthand how far the current standard of care falls short for patients with schizophrenia and depression. The science underpinning Syremis’ pipeline gives me confidence that we can make meaningful progress and help address significant unmet needs.”
“Aaron’s unique combination of frontline clinical experience and neuropsychiatric drug development expertise strengthens Syremis,” Co-Founder and CEO Elisabeth Kogan said. “His understanding of patient need and how to prove clinical impact is exactly the perspective [to] drive our programs forward.”
Syremis’ lead program, ST-905, is a dual M1/M4 agonist currently in Phase I development for schizophrenia, among other conditions.
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