AavantiBio, a gene therapy company focused on transforming the lives of patients with rare genetic diseases, and Aldevron, active in the custom development and manufacture of plasmid DNA, proteins and mRNA for the biotech industry, formed a long-term partnership for the supply of plasmid DNA that will enable AavantiBio to advance its platform of innovative gene transfer therapies.
 
Aldevron will provide plasmids for AavantiBio’s future gene therapy programs, including the company’s neuromuscular and CNS pipeline programs. In addition, Aldevron will provide AavantiBio with plasmid supply materials for Proof-of-Concept studies (POC) to be produced within AavantiBio’s planned vector core facility, which is expected to open later this year and will supply pre-clinical and analytical material for future pipeline products. The partnership with Aldevron further enhances AavantiBio’s strategic capabilities as the company looks to develop novel gene therapies for patients with rare genetic diseases.
 
“This collaboration is an important milestone in AavantiBio’s evolution as we seek to advance our pipeline of gene therapy candidates which have the potential to become next-generation, life-changing genetic medicines,” said Bo Cumbo, president and CEO, AavantiBio. “Partnering with Aldevron, the premier plasmid DNA manufacturer in the world, and leveraging their proven manufacturing expertise, will support AavantiBio’s pre-clinical and clinical development efforts and supports our strategic plans to bring high impact, transformational therapies to patients with rare genetic diseases.”
 
Aldevron will develop and optimize the plasmid DNA in its pre-clinical research grade facility, moving through to its GMP-Source and GMP manufacturing facility in Fargo, ND.
 
Kevin Ballinger, CEO, Aldevron, said, “Aldevron is proud to support AavantiBio with the development and supply of their plasmid DNA needs as part of their efforts to transform the lives of patients facing a rare disease. Since 1998, we have been providing our clients with the highest quality biologics and industry expertise they need to help give hope to millions. We look forward to working together through this long-term, strategic partnership.”