Abzena, a CDMO for biologics and bioconjugates, has launched AbZelect and AbZelectPRO cell line development (CLD) platforms for the generation of production cell lines for manufacture of antibodies and recombinant proteins. 
 
AbZelect and AbZelectPRO platforms are designed to enable the rapid generation and selection of high-yielding mammalian CHO cell lines for therapeutic protein and recombinant vaccine production. Designed for traditional protein programs, such as antibodies, AbZelect is optimized across the three key areas of vector, host cell line, and process. According to the company, it provides improved cell doubling times, viable cell densities, and robust and stable cell lines. 
 
To achieve the highest production levels, AbZelectPRO combines AbZelect with ProteoNic’s 2G UNic premium vector technology. This aims to boost expression levels and generate higher producing, stable cell lines expressing proteins including bispecifics, fusion proteins, and other novel modalities.
 
According to the company, by streamlining the CLD process, these platforms reduce timelines from DNA to research cell banks to 15 weeks with exceptional productivity levels. 
 
Matthew Stober, Chief Executive Officer at Abzena said, “The higher productivity that’s achievable with the AbZelect™ and AbZelectPRO™ platforms means we can produce more drug substances per manufacturing run. These efficiencies will not only expand our capacity and help to reduce the cost of goods for our customers but also reduce the time it takes to get new and critical therapies to patients in need.”