Bormioli Pharma, a glass and plastic packaging manufacturer for the pharmaceutical sector, has introduced its innovative dual-chamber AccuRec system as a solution for unstable drug formulations and to deliver value-added medicines.

AccuRec is a dual-chamber packaging system that lets patients reconstitute, in a few steps, a range of oral drug products right in the packaging container. Pre-dosed solvent and drug powder are stored in separate chambers in a tamper-evident and child-proof package; a simple twist releases the powder into the solvent at time of dosing.

The AccuRec system, and the precise, effective reconstitution it allows, maximizes drug stability in reconstituted oral medicines by eliminating the need to include excipients with the active ingredient. Excipients are traditionally used in pharmaceuticals to make drugs more stable, but this can contribute to additional adverse side effects from drug toxicity, allergy, or intolerance . AccuRec circumvents the need for excipients because the chambers prevent active ingredients from contacting and interacting with the solvent until the moment of administration.

Until now, reconstitution at the time of dosing has been complex and challenging for patients. The easy-to-use AccuRec system helps eliminate the chance for human error by providing guided self-administration and effective mixing of pre-dosed solvent and drug powder.

AccuRec’s design makes it attractive for value-added medicines, which are medicines based on known molecules that address health care needs and deliver relevant improvements for patients, health care professionals, and/or payers. The value of existing medicine can be enhanced through a broad range of processes, including reformulation/repackaging.

AccuRec is designed to improve the patient experience with easier, simplified drug reconstitution. Turning a complex procedure like reconstitution into an easy one can lead to better patient compliance and offer pharmaceutical companies new ways to solve dosing and compliance problems.

“We are very excited by the potential AccuRec offers to stakeholders across healthcare, from payers to patients,” says Anna Malori, business development manager, Bormioli Pharma. “Its simplicity, accuracy, and design make it a suitable solution for drug stability issues and an attractive option for value-added medicines.”

Bormioli Pharma is exhibiting AccuRec and a range of Type I Glass containers in Booth 2001 at CPhI North America. The first at-scale commercial rollout of the AccuRec system with a drug manufacturer is expected in the second quarter of 2018.