GenScript USA Inc., a life-science research tools and services provider, has introduced a new research use only (RUO) and pre-clinical messenger RNA (mRNA) synthesis service for biopharma research and development teams. By applying decades of experience in molecular biology, GenScript now offers a single-vendor gene-to-mRNA service that delivers custom mRNA within six to eight weeks.

mRNA provides new therapeutic opportunities for a range of diseases, and scientists need expedited access to robust, custom mRNA to synthesize the proteins used to engineer personalized medicines. But, until now, development of mRNA involved contracting with several different specialist suppliers.

In contrast, GenScript’s IVT mRNA service spans the entire workflow, from gene synthesis to mRNA production. This simple and expedited mRNA manufacturing workflow expands the possibilities for personalized medicines such as patient-specific cancer vaccines or protein replacement for rare diseases.

“GenScript has brings decades of deep technical expertise and a reputation for routinely producing customized nucleic acids for biopharma, academic, and industry clients worldwide,” said Ray Chen, president, GenScript USA Life Science Group. “The new IVT mRNA production service solves mRNA researchers’ challenges of sourcing and communicating among multiple vendors and de-risks the synthesis of highly optimized mRNA designs.”

Service highlights

• GenScript accelerates mRNA research with optimized mRNA production workflow — from gene to mRNA in 6-8 weeks
• Eliminates the need to provide mRNA expression vectors: just provide open reading frames (ORFs); GenScript will manage all the steps to successful custom mRNA synthesis
• GenScript’s integrated gene synthesis, linearization, and IVT process ensures high mRNA integrity and uniform poly(A) tails which results in enhanced expression efficiency.
• mRNAs produced at GenScript are optimized with our proprietary production platform, ensuring the quality and expression efficiency of your mRNA.

Where to learn more

• Visit GenScript’s IVT mRNA services information page
• Download the GenScript IVT mRNA therapy modalities infographic poster