Gerresheimer showcased its Gx RTF ClearJect syringe made of cyclic olefin copolymer (COP) at CPhI 2016. The syringes, which are designed for sensitive drugs, are now being manufactured in Germany. The whole syringe, including the needle overmould, is produced in one single step.

The Gx RTF ClearJect syringe is made of COP because the material does not leach metal ions into the drug solution. COP has a high pH tolerance, and unlike glass, there is no change in pH value over time during storage. COP’s inert and break-resistant properties offer a safety advantage for sensitive and toxic APIs. The Gx RTF ClearJect syringe is also tungsten- and adhesive-free.

High elasticity in comparison to similar materials also enhances the Dupont impact strength of COP syringes. The use of a high-viscosity silicon oil to coat the inside of the syringe barrel reduces the level of syringe content contamination with silicon particles, and the integration of standardized closure components also offers the pharmaceutical manufacturer flexibility. The Gx RTF ClearJect syringe comes with standard needles, plungers, plunger heads, backstops, and closures.