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May 13, 2008
By: Tim Wright
Editor-in-Chief, Contract Pharma
HollisterStier Laboratories has completed the construction of a full-service 6,000-sq.-ft. lab that includes analytical testing services with an analytical chemistry department. The lab is part of the company’s $42 million, 71,000-sq.-ft. facility-wide expansion project that more than doubles current manufacturing capacity. The company has also expanded its 172,000-sq-.ft. facility to include a new Small Volume Parenterals (SVP) line to aseptically fill liquid and lyophi¬lized pharmaceutical products in vials ranging from 2mL through 200 mL in batch sizes from 20 to 3,000 liters. The new line (SVP II) houses a 25,500-sq.-ft. vial filling complex with a Bosch FLC 3080 vial filler equipped with a nondestructive automatic check weigh system, diaphragm filling pumps and speeds as high as 400 vpm. The line offers multiple options for compounding including aseptic compounding, portable compounding vessels, and large fixed compounding tanks. The vial inspection and packaging area includes inspection, labeling, Ink Jet coding and secondary packaging. SVP II is designed for multi-product manufacturing, both commercial and clinical trial material, with one product manufactured in the area at a time. SVP II includes advances in pharmaceutical technology such as automated non-destructive fill checks and ISO5 oversealing. In addition, two GEA lyophiliz¬ers will be added in a new ISO5/6 facility and ready for production in 1Q09. “The expansion of our facilities is a reflection of the successes that our organization has worked hard to achieve,” said Anthony Bonanzino, Ph.D., chief executive officer of HollisterStier. “We take pride in the quality and efficiency we provide our customers. Our reputation as world-class contract manufacturers has allowed for us to be in a position to expand upon our capabilities so that we can continue to best serve our customer-base.”
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