Juno Therapeutics and Thermo Fisher Scientific have entered into a partnership for Juno to use Thermo Fisher’s Cell Therapy Systems (CTS) activation reagents in the manufacturing of its chimeric antigen receptor T cell (CAR T) therapies. 

Under the seven-year nonexclusive licensing and supply agreement, Juno has obtained rights to use CTS Dynabeads CD3/CD28 magnetic beads as part of the clinical and commercial manufacturing processes for its current and future CAR T therapies. 

CTS Dynabeads activate and expand T cells that have been genetically engineered to recognize and fight cancer cells in each individual patient. The proprietary platform already enables research, development, and commercialization of other CAR T cell therapies globally by providing a scalable platform that streamlines production while ensuring high reproducibility.

“Juno aims to manufacture best-in-class CAR T therapies to help as many patients as we can,” said Ann L. Lee, Juno’s executive vice president of Technical Operations. “Thermo Fisher’s technology will help us do that and deliver on our promise to patients.”