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Innovative compaction simulator technology adds early-stage material characterization and scale-up capability to the KORSCH R&D product portfolio.
February 8, 2023
By: Kristin Brooks
Managing Editor, Contract Pharma
KORSCH AG, a provider of tablet press technology for product development, scale-up, high-speed production, multi-layer, continuous manufacturing, and high-containment applications, has acquired MEDELPHARM, a provider of compaction simulator technology. After a year of the company’s global strategic partnership, the acquisition leverages a combined 135-plus years of experience with small-scale, fully instrumented tablet compression equipment. The KORSCH R&D product portfolio addresses longstanding challenges, from early-stage powder characterization and formulation development, to predictive scale-up and production support. The combined KORSCH-MEDELPHARM R&D equipment lineup includes: XP 1: Robust single-punch tablet press with small batch capabilities STYL’One Nano: Benchtop compaction simulator with integrated analytical software, for single layer formulation development STYL’One Evo: Advanced compaction simulator with integrated analytical software and multi-layer capability, allowing R&D at production speed. XL 100: Small-scale rotary press for product development and clinical batch production Covering the full spectrum of tableting technology from single-layer to five-layer as well as core coating capabilities, the new R&D product equipment portfolio complements KORSCH’s multi-layer production machinery. Notably, the STYL’One Evo offers the ability to simulate all high-speed production presses to predict product performance with minimal material quantities. The combined R&D product line offers the latest in high-containment technology, with fully integrated dry containment (DryCon) and wash-in-place containment (WipCon) solutions across the full range of OEB 3, OEB 4, and OEB 5 applications. Like the MEDELPHARM Science Lab in Lyon, France, the KORSCH Innovation Centers in Berlin, Boston, and Hyderabad have installed the STYL’One Evo and STYL’One Nano compaction simulators for demonstration, testing, and product trials with predictive results. The Science Lab in Lyon and the KORSCH Innovation Center in Berlin also offer contract development services including formulation optimization, powder analysis, and material characterization.
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