Eli Lilly and Company plans to expand its manufacturing footprint in Indiana by investing $2.1 billion in two new manufacturing sites at Indiana’s LEAP Lebanon Innovation and Research District in Boone County.

These new facilities will expand Lilly’s manufacturing network for active ingredients and new therapeutic modalities, such as genetic medicines.

“More than 146 years after our founding, Lilly remains committed to investing and innovating in Indiana,” said David A. Ricks, Lilly’s chair and CEO. “These new sites will add capacity in support of our growing pipeline of innovative medicines, while also creating more high-tech jobs for Hoosiers. We are pleased to be a founding investor at the LEAP Lebanon Innovation District.”

Over the past eight years, Lilly has delivered 17 new medicines, including tirzepatide (approved by the FDA as Mounjaro) for the treatment of type 2 diabetes, and aims to introduce four potential new medicines in the next two years. These new sites will support increased demand for existing Lilly products and play a key role in bringing Lilly’s clinical pipeline to patients around the world.

The proposed project is expected to create up to 500 new Lilly roles with an additional four indirect jobs for every Lilly position created, based on industry data. An estimated 1,500 construction jobs will be required while the facilities are being built.

“Lilly has been an anchor in Indiana’s economy for generations, and this announcement means they will continue to be here for generations,” said Indiana Governor Eric J. Holcomb. “I am incredibly proud Lilly continues to make exciting investments in Indiana that will better the lives and opportunities of Hoosiers for decades to come. And in turn, the very research and pharmaceutical manufacturing spearheaded here in our state will improve lives worldwide.”

Lilly’s most recent expansion in Indiana was announced in 2019 and capped a series of investments in research and manufacturing in and around Indianapolis. Those investments totaled more than $2.5 billion over five years and have created additional manufacturing jobs bringing the total current number of Lilly manufacturing employees in Indiana to more than 3,700.