The Ritedose Corporation Inc., a CDMO specializing in sterile Blow Fill Seal (BFS) production of unit dose solutions for the ophthalmic and respiratory markets, has partnered with Verona Pharma plc as the development and manufacturing partner of Ohtuvayre, a new novel product for Chronic Obstructive Pulmonary Disease (COPD).
 
The U.S. FDA approved Ohtuvayre on June 26 for the maintenance treatment of COPD in adult patients. It is the first inhaled product with a novel mechanism of action available for the maintenance treatment of COPD in more than 20 years.
 
Ohtuvayre is delivered through a standard jet nebulizer and is expected to redefine the treatment paradigm for COPD. Despite maintenance therapy in multiple combinations, most COPD patients grapple with daily symptoms including breathlessness and persistent coughing. Ohtuvayre, an innovative first-in-class PDE3 and PDE4 inhibitor, offers a needed, unique, important advancement in the treatment of COPD.
 
“Ritedose is the leading manufacturer of inhaled products for asthma and COPD. We are proud to partner with Verona Pharma for the development and manufacturing of Ohtuvayre. We have served the respiratory market for over 25 years and are excited to help bring this novel therapy to commercialization. We have the resources to deliver significant doses of Ohtuvayre on time, every time,” said Jody Chastain, president and CEO of The Ritedose Corporation.
 
“Ohtuvayre is a significant advancement in the treatment of COPD. We believe Ohtuvayre’s novel profile can change the treatment paradigm for COPD, and we wanted to partner with Ritedose to ensure the highest manufacturing quality. The COPD community deserves nothing less,” said David Zaccardelli, Pharm. D., President and CEO of Verona Pharma.