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An interim analysis by an independent data monitoring committee determined that the MOBILIZE study is unlikely to provide sufficient efficacy.
June 10, 2026
By: Charlie Sternberg
Associate Editor
Sanofi has discontinued its riliprubart MOBILIZE phase 3 study in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) following an interim analysis by an independent data monitoring committee, which determined that the study is “unlikely to provide sufficient efficacy.”
No safety signals related to riliprubart were identified as part of this interim analysis. The continuation of other ongoing studies with riliprubart, including the VITALIZE phase 3 study in IVIg-treated patients with CIDP, will be evaluated accordingly.
Sanofi says it will work closely with investigators and site teams to ensure a wind-down of the MOBILIZE study, with appropriate transition of care for all enrolled patients. The company will also conduct a thorough analysis of the MOBILIZE data to inform future research directions and contribute to the broader scientific understanding of CIDP.
Sanofi recently announced a new agreement with Owkin, an agentic AI company pioneering biological artificial superintelligence for drug discovery and development.
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