Solvay’s Udel P-1700 polysulfone (PSU) was chosen for the new series of bioprocess fittings, designed for biocompatibility, transparency, strength and rigidity, broad temperature range and compatibility with gamma radiation (up to 50 kGy) and steam sterilization.

Udel P-1700 PSU is designed to withstand the required operating temperature range of -40C to 138C (-40°F to 280°F), enabling the aseptic disconnects to be used in cryogenic conditions and be steam sterilized. The material’s transparency allows processors to observe the flow of liquid through the connectors, and its combination of high heat resistance and hydrolytic stability provide an important advantage over polycarbonate (PC), which is highly susceptible to stress cracking. Udel P-1700 PSU is animal-derived component free (ADCF), and it meets USP Class IV requirements for biocompatibility. In addition, components can be molded to tight tolerances with minimal flash and scrap.
 
“Adopting Solvay’s high-performance Udel PSU meant a significant shift from the polyolefins we’ve historically used,” said Ken Davis, global product line manager for biopharmaceuticals at Nordson MEDICAL. “Solvay’s technical support and processing guidance made the transition to this new material smooth and easy. It’s performing beautifully and we look forward to future collaborations with Solvay on other products.”

According to the company, the Spaulding Series Aseptic Disconnects provide a leak-free connection, eliminating the need for pinch clamps and tube welders. Smooth disconnects are achievable with the easy-to-use design, and valuable fluids are protected by valves that automatically shut off flow when the fittings are disconnected, according to the company. Validation and test results confirm their suitability in pre- and post-sterilized systems. The connectors are suited for processing biopharmaceuticals, vaccines and active pharmaceutical ingredients.

“Solvay is committed to supplying next-generation polymers to support advancements in bioprocessing, cell and gene therapies and pharmaceutical processing,” said Eva Heintz, global marketing manager for Healthcare at Solvay’s Specialty Polymers global business unit. “By serving as a true partner to companies like Nordson MEDICAL, Solvay helps to match key material attributes to specific application requirements.”