• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Manufacturing
    • Packaging
    • Development
    • Compliance
    • Top 25
    • Directory
    • Microsites
    • Events
    • More
  • Magazine
  • News
  • Manufacturing
  • Packaging
  • Development
  • Compliance
  • Top 25
  • Directory
  • Microsites
  • Events
  • Current / Back Issue
    Features
    Editorial
    Columns
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Subscribe Now
    Advertise Now
    Top Features
    Bye-Bye China?

    Decentralized Trials Fuel AI Revolution in Clinical Research

    Self-Medication: Flexibility for Patients and Drug Manufacturers

    The Single-Use Mixing Landscape: Evaluating Your Options

    DCAT President Talks COVID-19, Drug Manufacturing and Innovation
    Breaking News
    Online Exclusives
    Industry News
    Collaborations & Alliances
    Promotions & Moves
    Trials & Filings
    Financial Reports
    Bio News & Views
    Custom Sourcing News
    Packaging & Tracking
    CRO News
    Live From Shows
    Top News
    Stevanato Group Launches After-sales Service Offering

    X-Chem Acquires IntelliSyn and AviSyn

    Aphena’s $21M Cookeville Expansion Nears Completion

    BioMed X, Janssen Enter Oral Drug Delivery Alliance

    Care Access Research, AstraZeneca Partner on COVID-19 Antibody Trial
    APIs
    Aseptic Processing
    Cleaning Validation
    Clinical Trial Materials
    Cytotoxics and High Potency Manufacturing
    Equipment
    Excipients
    Extractables and Leachables
    Facilities
    Fill/Finish
    Lyophilization
    Parenterals
    Process Development
    Process Validation
    Risk Management
    Scale-up/ Technology Transfer
    Solid Dosage/ Creams/ Ointments

    Aphena’s $21M Cookeville Expansion Nears Completion

    PromoCell Receives EXCiPACT Certification

    Civica to Build an Essential Medicines Manufacturing Facility in Virginia

    Humanigen, Emergent Enter Covid-19 Partnership

    Samsung Bioepis Opens New Headquarters
    Capsules
    Cold Chain Management
    Injectables
    Logistics
    Serialization
    Solid Dosage / Semi-solids
    Supply Chain
    Vials

    Aphena’s $21M Cookeville Expansion Nears Completion

    Civica to Build an Essential Medicines Manufacturing Facility in Virginia

    WDSrx Expands Warehouse Network

    Catalent Acquires Acorda’s INBRIJA Manufacturing Operations

    Varcode, PL Developments Form Strategic ‘Smart Tag’ Pact
    Analytical Services
    Bioanalytical Services
    Bioassay Developement
    Biologics, Proteins, Vaccines
    Biosimilars
    Chemistry
    Clinical Trials
    Drug Delivery
    Drug Development
    Drug Discovery
    Formulation Development
    Information Technology
    Laboratory Testing
    Methods Development
    Microbiology
    Preclinical Outsourcing
    R&D
    Toxicology

    The Future of Clinical Trials Series: Part II

    X-Chem Acquires IntelliSyn and AviSyn

    Care Access Research, AstraZeneca Partner on COVID-19 Antibody Trial

    Caprion-HistoGeneX Rebrands as CellCarta

    Humanigen, Emergent Enter Covid-19 Partnership
    Filtration & Purification
    GMPs/GCPs
    Inspections
    QA/QC
    Regulatory Affairs
    Validation

    Top BioPharma Form Accumulus Synergy

    Global Biosciences Co. Selects ValGenesis VLMS

    Gene Therapy Co. Selects ValGenesis' SaaS Platform

    The Year of COVID: How FDA Coped with a Worldwide Pandemic in 2020 and What to Expect in 2021

    Samsung Biologics Adopts Veeva Vault QMS to Unify Quality Management
    Companies
    Categories
    Corporate Capabilities
    Add New Company
    Contract Service Directory Companies
    Almac Group

    Cytovance Biologics

    Alcami

    Syngene

    Reed-Lane
    Companies
    News Releases
    Posters
    Brochures
    Services
    Videos
    Case Study
    White Papers
    Jobs
    Contract Service Directory Companies
    Baxter BioPharma Solutions

    PCI Pharma Services

    Syngene

    Reed-Lane

    Emergent BioSolutions
    Webinars
    Live From Shows
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
      • Enewsletter Archive
      • Digital Edition
    • Directory
      • Companies
      • Categories
      • Corporate Capabilities
      • Add Your Company
    • Manufacturing
      • APIs
      • Aseptic Processing
      • Cleaning Validation
      • Clinical Trial Materials
      • Cytotoxics and High Potency Manufacturing
      • Equipment
      • Excipients
      • Extractables and Leachables
      • Facilities
      • Fill/Finish
      • Lyophilization
      • Parenterals
      • Process Development
      • Process Validation
      • Risk Management
      • Scale-up/ Technology Transfer
      • Solid Dosage/ Creams/ Ointments
      • cGMP Manufacture
    • Packaging
      • Capsules
      • Cold Chain Management
      • Injectables
      • Logistics
      • Serialization
      • Solid Dosage / Semi-solids
      • Supply Chain
      • Vials
    • Development
      • Analytical Services
      • Bioanalytical Services
      • Bioassay Developement
      • Biologics, Proteins, Vaccines
      • Biosimilars
      • Chemistry
      • Clinical Trials
      • Drug Delivery
      • Drug Development
      • Drug Discovery
      • Formulation Development
      • Information Technology
      • Laboratory Testing
      • Methods Development
      • Microbiology
      • Preclinical Outsourcing
      • R&D
      • Toxicology
    • Compliance
      • Filtration & Purification
      • GMPs/GCPs
      • Inspections
      • QA/QC
      • Regulatory Affairs
      • Validation
    • Top 25 Pharma & BioPharma
    • Contract Pharma Direct
    • Breaking News
    • Online Exclusives
    • Slideshows
    • Experts Opinions
    • Surveys
      • Outsourcing Survey
      • Salary Survey
    • Glossary
    • Videos
    • Podcasts
    • White Papers
    • Infographics
    • Contract Pharma Conference
      • Contract Pharma Conference
      • Speakers
      • Exhibitors
      • Conference Sessions
    • Supplier Microsite
      • Companies
      • News Releases
      • Posters
      • Brochures
      • Services
      • Videos
      • Case Study
      • White Papers
    • eBook
    • Webinars
    • Events
      • Industry Events
      • Live from Show Events
      • Webinars
    • Classifieds / Job Bank
      • Classifieds
      • Job Bank
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Exelixis, Genentech Enter Onco-Development Pact

    ...

    Related CONTENT
    • Corvus, Genentech Expand Clinical Collaboration
    • Biogen Names CEO
    • Genentech Extends Phylogica Research Pact
    • Biogen Spin-off Bioverativ Adds Management
    • Halozyme, Genentech in Broad Clinical Collaboration
    01.03.07
    Exelixis, Inc. has entered into an agreement with Genentech, Inc. for the worldwide co-development of XL518, a small-molecule inhibitor of MEK, which is a key component associated with tumors. Inappropriate activation of MEK/ERK can promote cell growth in the absence of exogenous growth factors. Exelixis submitted an IND for XL518 in December 2006.

    Under the terms of the agreement, Exelixis will receive upfront and milestone payments totaling $40 million. Exelixis is responsible for developing XL518 through the end of Phase I. If Genentech exercises its option to further develop XL518, Exelixis will receive an additional payment and Genentech will be responsible for further development. Exelixis has the option to co-promote in the U.S. and will share a portion of the marketing and commercialization costs, as well as an initial equal share in profits in the U.S., which will decrease as sales increase. Exelixis will receive royalties on any sales of the product outside the U.S.

    "Genentech is a leading innovator of important new cancer therapies, and we believe that this collaboration validates the significant potential of XL518 to be the first in a new class of drugs targeting critical intracellular signaling pathways," said George A. Scangos, Ph.D., president and chief executive officer of Exelixis. "This collaboration also combines our world class drug discovery and development platform with Genentech's proven track record in commercializing novel compounds that positively impact the lives of patients with cancer."
    Related Searches
    • Drug Discovery
    Suggested For You
    Corvus, Genentech Expand Clinical Collaboration Corvus, Genentech Expand Clinical Collaboration
    Biogen Names CEO Biogen Names CEO
    Genentech Extends Phylogica Research Pact Genentech Extends Phylogica Research Pact
    Biogen Spin-off Bioverativ Adds Management Biogen Spin-off Bioverativ Adds Management
    Halozyme, Genentech in Broad Clinical Collaboration Halozyme, Genentech in Broad Clinical Collaboration
    Charles River, Genentech Extend Discovery Alliance Charles River, Genentech Extend Discovery Alliance
    Catalent Biologics Appoints R&D Director Catalent Biologics Appoints R&D Director
    Exelixis, Ipsen in Exclusive Cabozantinib Alliance Exelixis, Ipsen in Exclusive Cabozantinib Alliance
    Biogen Idec Changes Name to Biogen Biogen Idec Changes Name to Biogen
    Exelixis Begins CRPC Trial Exelixis Begins CRPC Trial
    Trials & Filings in Brief: Dec. 2, 2013 Trials & Filings in Brief: Dec. 2, 2013
    Exelixis, BMS Enter Multiple Drug Pacts Exelixis, BMS Enter Multiple Drug Pacts
    Array, Novaris in MEK Pact Array, Novaris in MEK Pact
    Exelixis, BMS Brain Cancer Drug Shows Promise Exelixis, BMS Brain Cancer Drug Shows Promise
    Genentech To Develop Exelixis Cancer Drug Genentech To Develop Exelixis Cancer Drug

    Related Breaking News

    • Breaking News | Drug Discovery | Industry News | Preclinical Outsourcing
      X-Chem Acquires IntelliSyn and AviSyn

      X-Chem Acquires IntelliSyn and AviSyn

      Acquisitions allow the company to offer services for screening, hit validation and lead optimization on existing and new markets.
      Kristin Brooks 01.26.21

    • Breaking News | Drug Development | Drug Discovery | Industry News
      Lilly Completes $1B Acquisition of Prevail

      Lilly Completes $1B Acquisition of Prevail

      Adds new modality for drug discovery and development and creates a gene therapy program with neuroscience assets.
      Kristin Brooks 01.22.21

    • Breaking News | Collaborations & Alliances | Drug Discovery
      Metrion, LifeArc Extend Neuroscience Alliance

      Metrion, LifeArc Extend Neuroscience Alliance

      Collaboration extended for another 12 months after successfully progressing into late stage hit-to-lead optimization phase.
      Contract Pharma Staff 01.18.21


    • Breaking News | Collaborations & Alliances | Drug Development | Drug Discovery
      Janssen, TenNor Enter NTM Research Pact

      Janssen, TenNor Enter NTM Research Pact

      To leverage TenNor’s multitargeting drug conjugation platform to discover new therapies to treat nontuberculous mycobacteria diseases.
      Contract Pharma Staff 01.18.21

    • Breaking News | Collaborations & Alliances | Drug Development | Drug Discovery | Industry News
      EVOQ Therapeutics and Amgen Partner

      EVOQ Therapeutics and Amgen Partner

      Collaborate on the discovery and development of novel drugs for autoimmune disorders.
      Contract Pharma Staff 01.13.21

    • Breaking News | Collaborations & Alliances | Drug Discovery | Industry News | R&D
      Almac Sciences Secures Support from Invest NI

      Almac Sciences Secures Support from Invest NI

      Accelerates enzyme discovery program.
      Contract Pharma Staff 01.13.21


    • Breaking News | Collaborations & Alliances | Drug Discovery | Industry News | R&D
      Mogrify Enters Research Collaboration with MRC LMB

      Mogrify Enters Research Collaboration with MRC LMB

      Research project aims to develop novel protein expression systems via cell reprogramming.
      Contract Pharma Staff 01.11.21

    • Breaking News | Collaborations & Alliances | Drug Discovery | Industry News
      Servier and X-Chem Enter Drug Discovery Collaboration

      Servier and X-Chem Enter Drug Discovery Collaboration

      Partner to identify and develop novel small molecules for the treatment of neurological disorders.
      Contract Pharma Staff 01.07.21

    • Breaking News | CRO News | Drug Discovery | Preclinical Outsourcing
      Charles River Labs Acquires Distributed Bio

      Charles River Labs Acquires Distributed Bio

      Establishes integrated, large molecule discovery platform.
      Contract Pharma Staff 01.04.21


    • Breaking News | Collaborations & Alliances | Drug Development | Drug Discovery
      Evotec, BMS Advance Targeted Protein Degradation Projects

      Evotec, BMS Advance Targeted Protein Degradation Projects

      The first two targets transition into drug discovery after completing a comprehensive target validation process.
      Contract Pharma Staff 12.17.20

    • Breaking News | Collaborations & Alliances | CRO News | Drug Discovery | Industry News | R&D
      Evotec and Sartorius Partner with Curexsys

      Evotec and Sartorius Partner with Curexsys

      Leverage IPSC platform for scalable manufacturing of Curexsys' exosome-based therapeutics.
      Contract Pharma Staff 12.09.20

    • Breaking News | Collaborations & Alliances | Drug Discovery | Industry News
      Syngene and 3DC Sign 5-year Collaboration

      Syngene and 3DC Sign 5-year Collaboration

      Partner on discovery projects, from target validation through to pharmacological proof of concept and preclinical evaluation.
      Contract Pharma Staff 11.24.20


    • Breaking News | CRO News | Drug Discovery | Industry News
      MercachemSyncom Acquires Admescope

      MercachemSyncom Acquires Admescope

      Significantly expands its capabilities for in vitro and in vivo studies.
      Contract Pharma Staff 11.10.20

    • Bio News | Breaking News | Collaborations & Alliances | Drug Discovery | Industry News
      Eurofins Discovery Collaborates with Swiss Biotech Amphilix

      Eurofins Discovery Collaborates with Swiss Biotech Amphilix

      To support a program aimed at identifying a treatment modulating key disease mechanisms.
      Contract Pharma Staff 11.03.20

    • Analytical Services | Biologics, Proteins, Vaccines | Breaking News | Drug Development | Drug Discovery | Industry News
      Thermo Fisher, Symphogen Extend Development Pact

      Thermo Fisher, Symphogen Extend Development Pact

      Will support the development of cancer treatments through optimization of protein characterization and quality monitoring mass spectrometry.
      Contract Pharma Staff 10.29.20

    Trending
    • Integrated Continuous Manufacturing ICM
    • Humanigen, Emergent Enter Covid-19 Partnership
    • Samsung Bioepis Opens New Headquarters
    • CDMO Northway Biotech Expands In U.S.
    • CONTINUUS Awarded $69.3M DoD Grant
    Breaking News
    • Stevanato Group Launches After-sales Service Offering
    • X-Chem Acquires IntelliSyn and AviSyn
    • Aphena’s $21M Cookeville Expansion Nears Completion
    • BioMed X, Janssen Enter Oral Drug Delivery Alliance
    • Care Access Research, AstraZeneca Partner on COVID-19 Antibody Trial
    View Breaking News >
    CURRENT ISSUE

    November/December 2020

    • Modeling Process Safety Workflows in Pharmaceutical Manufacturing Scale-Up
    • Ensuring Quality During the Transfer and Scale Up of Rx Drugs
    • Inspecting the Unexpected
    • Cold Chain Trends
    • Catering for the Complex
    • Biopharma Contract Manufacturing: Robust Growth Ahead
    • DCAT President Talks COVID-19, Drug Manufacturing and Innovation
    • The Single-Use Mixing Landscape: Evaluating Your Options
    • Self-Medication: Flexibility for Patients and Drug Manufacturers
    • Decentralized Trials Fuel AI Revolution in Clinical Research
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    MIND and Mediterranean Diets Linked to Later Onset of Parkinson’s Disease
    Kerry Launches Web-Based Tool for Plant-Based Formulation Challenges
    Wiley’s Finest Earns Accolades for Taste of Omega-3 Products
    Coatings World

    Latest Breaking News From Coatings World

    Scott McLaughlin to Race in PPG Colors During Rookie INDYCAR Season
    Vink Chemicals Offers parmetol PSG
    Minwax Announces Vintage Blue as 2021 Color of the Year
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Butterfly Network Appoints New Leader
    BD Names Chairman of Board
    Interplex Acquires OCP Group
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Stevanato Group Launches After-sales Service Offering
    X-Chem Acquires IntelliSyn and AviSyn
    Aphena’s $21M Cookeville Expansion Nears Completion
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    The Estée Lauder Companies Announces Game-Changing Sustainability Goals for Travel Retail
    Aura Introduces Customizable Hair Care
    Corpack Creates Custom Packaging for Marlies Möller Hair Care Line
    Happi

    Latest Breaking News From Happi

    Nice-Pak Receives EPA Approval for Disinfectant Wipes
    Symrise Shares 2020 Sales Figures
    Harry’s Launches ‘Headquarters’
    Ink World

    Latest Breaking News From Ink World

    Epson Partner Creates Label Applicators for Pharmaceutical Products
    Smurfit Kappa Sets New Sustainability Targets with Better Planet 2050
    Paragon Expands Direct Mail Capabilities with Ricoh Pro VC70000
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Great Lakes Label debuts new website
    Epson partner creates label applicators for pharmaceutical products
    ACTEGA removes chemicals from laminating adhesives
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    American Made Production Equipment for Mask Manufacturers
    Kimberly-Clark Releases Q4, Full Year Results
    Freudenberg to Establish Apparel Interlining Competence Centers
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Spinal Elements' Lucent XP-Curved Expandable TLIF Gains FDA Nod
    FDA OKs OrthoSpin's 2nd Gen Robotic, Digital External Fixation System
    Nextremity Solutions Enters Supply Agreement with Fort Wayne Metals
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    North American Semiconductor Equipment Industry Posts December 2020 Billings
    First Solar Signs Definitive Agreement to Sell US Development Platform to Leeward
    PRINTING United Alliance Announces TAGA Presents Virtual Event

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login