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    Breaking News

    Daiichi Sankyo Invests 15B Yen in ADC Mfg. Expansion

    To optimize and enhance ADC manufacturing capabilities at three plants in Japan

    04.27.17
    Daiichi Sankyo Co., Ltd. is making an initial 15 billion yen investment to optimize and enhance its manufacturing capabilities to support its antibody drug conjugate (ADC) pipeline. 
     
    The company will build new and refurbish manufacturing lines at three of its manufacturing plants in Japan. These improvements will expand the production of fully synthesized ADCs and help to ensure a stable supply for future investigational and commercial use.
     
    Antibody drug conjugates (ADCs) are a type of targeted cancer medicine that deliver cytotoxic chemotherapy ("payload") directly to cancer cells via a linker attached to a monoclonal antibody that binds to a specific target expressed on cancer cells. Daiichi Sankyo's ADC technology is designed to deliver enhanced cancer cell destruction with less systemic exposure to the cytotoxic payload.  
     
    Its ADC franchise currently consists of six ADCs, including DS-8201 and U3-1402 in Phase I development, DS-7300, DS-1062 and two other ADCs with undisclosed targets in preclinical development. 
     
    "This strategic investment will bolster our leadership and expertise in ADC manufacturing, as we apply our proprietary ADC technology to more than two dozen biologics in preclinical or early stage development," said Katsumi Fujimoto, Ph.D., senior executive officer, head of Supply Chain Division, Daiichi Sankyo. "Our manufacturing capacities will more than triple by 2021, affording us greater flexibility for research and development, and strengthening our anticipated future commercial production."
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    Breaking News
    • Abzena, ProteoNic Partner to Offer Enhanced CHO Cell Line Platform
    • AQEMIA Inks $140M Small Molecule Deal with Sanofi
    • Hoth Therapeutics, WuXi STA Complete Manufacturing of HT-KIT
    • Körber, LabWare Expand LIMS Partnership
    • Aenova Expands High-Volume Solids Site in Germany
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    CURRENT ISSUE

    November/December 2023

    • After the Scope of Work is Complete
    • Top 50 Biopharma Products Drive Growth in Contract Manufacturing
    • Meeting Manufacturing Demand in the New Era of mRNA Technologies
    • Protein Therapeutics to Amp Up Outsourcing in Animal Health
    • ABCs of ADCs: A Brief Primer
    • Developing HPAPIs: Leveraging Classification Systems to Mitigate Risk
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    • The 22nd Annual Contract Pharma Contracting & Outsourcing Conference and Tabletop exhibition
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