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Enter into license agreement to develop four LiquiTime or Micropump products
February 12, 2018
By: Tim Wright
Editor-in-Chief, Contract Pharma
Avadel Pharmaceuticals has entered into an asset purchase agreement with Cerecor, whereby Cerecor will acquire the Avadel pediatric portfolio. In connection with this transaction, Avadel and Cerecor will enter into a license and development agreement pursuant to which Avadel will develop up to four product formulations for Cerecor using Avadel’s LiquiTime and Micropump technologies. Under the asset purchase agreement, Cerecor will acquire the company’s four commercial pediatric products, Karbinal ER, Cefaclor for oral suspension, Flexichamber and AcipHex Sprinkle. “We made significant progress developing our pediatric business over the last two years,” said Mike Anderson, chief executive officer, Avadel. “The script growth and revenue numbers were up substantially in 2017, particularly for Karbinal ER. However, after strategically evaluating our business objectives, we have made the decision to focus our efforts on expanding our urology, sleep and hospital-based products. Our pediatric products align with Cerecor’s objective to become a leading U.S. pediatric pharmaceutical company and with the addition of our sales team will expand their commercial footprint.” Mr. Anderson continued, “We will also enter into a license and development agreement to provide four new pediatric-focused product formulations using our Micropump and LiquiTime technologies to be selected by Cerecor. We believe they will be an excellent commercial partner and our team looks forward to working together during the development process.” Under the development agreement, Avadel expects to complete the initial bioequivalence studies within 18 months. Cerecor will reimburse Avadel for any costs associated with the development of the four products in excess of $1 million and, upon transfer of the product formulations, will assume all remaining development costs and responsibilities associated with regulatory approval and marketing. If any products receive approval, Cerecor will pay Avadel quarterly royalties based on a percentage of net sales in the mid-single digits.
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