Explore recent issues of Contract Pharma covering key industry trends.
Read the full digital version of our magazine online.
Stay informed! Subscribe to Contract Pharma for industry news and analysis.
Get the latest updates and breaking news from the pharmaceutical and biopharmaceutical industry.
Discover the newest partnerships and collaborations within the pharma sector.
Keep track of key executive moves and promotions in the pharma and biopharma industry.
Updates on the latest clinical trials and regulatory filings.
Stay informed with the latest financial reports and updates in the pharma industry.
Expert Q&A sessions addressing crucial topics in the pharmaceutical and biopharmaceutical world.
In-depth articles and features covering critical industry developments.
Access exclusive industry insights, interviews, and in-depth analysis.
Insights and analysis from industry experts on current pharma issues.
A one-on-one video interview between our editorial teams and industry leaders.
Listen to expert discussions and interviews in pharma and biopharma.
A detailed look at the leading US players in the global pharmaceutical and BioPharmaceutical industry.
Browse companies involved in pharmaceutical manufacturing and services.
Comprehensive company profiles featuring overviews, key statistics, services, and contact details.
A comprehensive glossary of terms used in the pharmaceutical and biopharmaceutical industry.
Watch in-depth videos featuring industry insights and developments.
Download in-depth eBooks covering various aspects of the pharma industry.
Access detailed whitepapers offering analysis on industry topics.
View and download brochures from companies in the pharmaceutical sector.
Explore content sponsored by industry leaders, providing valuable insights.
Stay updated with the latest press releases from pharma and biopharma companies.
Explore top companies showcasing innovative pharma solutions.
Meet the leaders driving innovation and collaboration.
Engage with sessions and panels on pharma’s key trends.
Hear from experts shaping the pharmaceutical industry.
Join online webinars discussing critical industry topics and trends.
A comprehensive calendar of key industry events around the globe.
Live coverage and updates from major pharma and biopharma shows.
Find advertising opportunities to reach your target audience with Contract Pharma.
Review the editorial standards and guidelines for content published on our site.
Understand how Contract Pharma handles your personal data.
View the terms and conditions for using the Contract Pharma website.
What are you searching for?
CEPI awards contract worth up to $36 million to develop Lassa virus vaccine
August 21, 2018
By: Tim Wright
Editor-in-Chief, Contract Pharma
CEPI (the Coalition for Epidemic Preparedness Innovations) has unveiled a new collaboration with Profectus BioSciences and Emergent BioSolutions under which they will receive up to $36 million to advance the development and manufacture of a vaccine against the Lassa virus-an estimated 100,000 to 300,000 cases of Lassa virus infection occur each year, according to the U.S. CDC. Under the terms of the Framework Partnering Agreement for the collaboration among the three parties, Profectus will receive development funding from CEPI for advancing its Lassa virus vaccine. CEPI will provide $4.3 million to support the first phase of the project, with options to invest up to a total of $36 million over five years, including procurement of the vaccine for stockpiling purposes. Emergent will provide technical and manufacturing support for the CEPI-funded program. Through a separate agreement with Profectus, Emergent has an exclusive option to license and to assume control of development activities for the Lassa-virus vaccine from Profectus. The global non-profit organization PATH will also be working with the consortium under a separate agreement with CEPI to work on clinical development. This is CEPI’s second award to the collaboration following an award in May, 2018, for the development of a Nipah virus vaccine. The Lassa virus is endemic in Benin, Ghana, Guinea, Liberia, Mali, Sierra Leone, and Nigeria, but probably exists in other West African countries as well. There is currently no approved vaccine that protects against Lassa virus. This year has seen outbreaks of Lassa virus in Liberia, Nigeria, Sierra Leone, and South Sudan, with Nigeria facing its largest ever outbreak of the disease. “With 472 confirmed cases to date and 121 deaths, 2018 has seen Nigeria battle its largest documented outbreak of Lassa virus on record,” said Richard Hatchett, chief executive officer, CEPI. “Lassa fever continues to be a threat to public health in many parts of West Africa and has clearly demonstrated its potential to cause severe epidemics. In view of its epidemic potential, the World Health Organization has identified Lassa virus as a priority pathogen that needs further research and development. But despite the urgent need, no approved vaccine against the virus is currently available. CEPI’s investment of up to $36 million, over a five-year period, adds another Lassa vaccine candidate to CEPI’s growing portfolio and demonstrates our commitment to addressing this terrible disease.” Thomas Lynch, chief executive officer, Profectus BioSciences, said, “Profectus is pleased to partner with CEPI, Emergent, and PATH in the development of our VesiculoVax-vectored vaccine to protect against Lassa fever. Jointly we can address the substantial unmet medical need of those living in, or travelling to, areas where Lassa virus is endemic.” “Through our collaboration with Profectus, CEPI, and PATH, Emergent is pleased to be part of the solution to provide medical countermeasures for emerging infectious diseases where there are none currently such as for Lassa fever,” said Daniel Abdun-Nabi, chief executive officer, Emergent BioSolutions. “Our Center for Innovation in Advanced Development and Manufacturing is designed for surge manufacturing during public health emergencies, when they count the most.”
Enter your account email.
A verification code was sent to your email, Enter the 6-digit code sent to your mail.
Didn't get the code? Check your spam folder or resend code
Set a new password for signing in and accessing your data.
Your Password has been Updated !