• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Manufacturing
    • Packaging
    • Development
    • Compliance
    • Top 25
    • Directory
    • Microsites
    • Events
    • More
  • Magazine
  • News
  • Manufacturing
  • Packaging
  • Development
  • Compliance
  • Top 25
  • Directory
  • Microsites
  • Events
  • Current / Back Issue
    Features
    Editorial
    Columns
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Subscribe Now
    Advertise Now
    Top Features
    Small Innovators & Niche CROs

    Focus on Science

    Rapid and Data Rich Chromatographic Method Development

    Preparing Your Post Pandemic Talent Strategy

    How Modern Near-Infrared Came to Be
    Breaking News
    Online Exclusives
    Industry News
    Collaborations & Alliances
    Promotions & Moves
    Trials & Filings
    Financial Reports
    Bio News & Views
    Custom Sourcing News
    Packaging & Tracking
    CRO News
    Live From Shows
    Top News
    Bristol Myers Squibb Expands at Cambridge Crossing

    Amgen Completes Five Prime Acquisition

    Sartorius Expands in the UK

    Obituary Notice: Russell “Russ” Haines

    Abenza Chooses North Carolina for New Biologics Manufacturing Site
    APIs
    Aseptic Processing
    Cleaning Validation
    Clinical Trial Materials
    Cytotoxics and High Potency Manufacturing
    Equipment
    Excipients
    Extractables and Leachables
    Facilities
    Fill/Finish
    Lyophilization
    Parenterals
    Process Development
    Process Validation
    Risk Management
    Scale-up/ Technology Transfer
    Solid Dosage/ Creams/ Ointments

    Abenza Chooses North Carolina for New Biologics Manufacturing Site

    Catalent Adds Cryogenic Capabilities at Philadelphia Facility

    Recro, Ensysce Expand Development and Manufacturing Partnership

    Metrics Names Stephanie Emory Associate Director of Pharma Development

    Albumedix Completes Commercial-Scale Mfg. Facility Expansion
    Capsules
    Cold Chain Management
    Injectables
    Logistics
    Serialization
    Solid Dosage / Semi-solids
    Supply Chain
    Vials

    Obituary Notice: Russell “Russ” Haines

    Catalent Adds Cryogenic Capabilities at Philadelphia Facility

    Cryoport Acquires Critical Transport Solutions Australia

    PharmParts – This Makes Sense!

    Securing Your API Supply Chain: Three Keys to Success
    Analytical Services
    Bioanalytical Services
    Bioassay Developement
    Biologics, Proteins, Vaccines
    Biosimilars
    Chemistry
    Clinical Trials
    Drug Delivery
    Drug Development
    Drug Discovery
    Formulation Development
    Information Technology
    Laboratory Testing
    Methods Development
    Microbiology
    Preclinical Outsourcing
    R&D
    Toxicology

    Bristol Myers Squibb Expands at Cambridge Crossing

    Amgen Completes Five Prime Acquisition

    Sartorius Expands in the UK

    Abenza Chooses North Carolina for New Biologics Manufacturing Site

    Arkema Recruits Dotmatics as its R&D Digitalization Partner
    Filtration & Purification
    GMPs/GCPs
    Inspections
    QA/QC
    Regulatory Affairs
    Validation

    Ensuring Pharma Manufacturing Quality

    What Will Change at FDA for 2021?

    RBQM Comes of Age: COVID as a Catalyst for Change

    Post-Pandemic Regulations

    Enteris BioPharma: Custom Solutions – From Bench to Market
    Companies
    Categories
    Corporate Capabilities
    Add New Company
    Contract Service Directory Companies
    Adare Pharma Solutions

    Almac Group

    Quotient Sciences

    Emergent BioSolutions

    Alcami
    Companies
    News Releases
    Posters
    Brochures
    Services
    Videos
    Case Study
    White Papers
    Jobs
    Contract Service Directory Companies
    Adare Pharma Solutions

    Quotient Sciences

    Emergent BioSolutions

    Alcami

    Syngene
    Webinars
    Live From Shows
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
      • Enewsletter Archive
      • Digital Edition
    • Directory
      • Companies
      • Categories
      • Corporate Capabilities
      • Add Your Company
    • Manufacturing
      • APIs
      • Aseptic Processing
      • Cleaning Validation
      • Clinical Trial Materials
      • Cytotoxics and High Potency Manufacturing
      • Equipment
      • Excipients
      • Extractables and Leachables
      • Facilities
      • Fill/Finish
      • Lyophilization
      • Parenterals
      • Process Development
      • Process Validation
      • Risk Management
      • Scale-up/ Technology Transfer
      • Solid Dosage/ Creams/ Ointments
      • cGMP Manufacture
    • Packaging
      • Capsules
      • Cold Chain Management
      • Injectables
      • Logistics
      • Serialization
      • Solid Dosage / Semi-solids
      • Supply Chain
      • Vials
    • Development
      • Analytical Services
      • Bioanalytical Services
      • Bioassay Developement
      • Biologics, Proteins, Vaccines
      • Biosimilars
      • Chemistry
      • Clinical Trials
      • Drug Delivery
      • Drug Development
      • Drug Discovery
      • Formulation Development
      • Information Technology
      • Laboratory Testing
      • Methods Development
      • Microbiology
      • Preclinical Outsourcing
      • R&D
      • Toxicology
    • Compliance
      • Filtration & Purification
      • GMPs/GCPs
      • Inspections
      • QA/QC
      • Regulatory Affairs
      • Validation
    • Top 25 Pharma & BioPharma
    • Contract Pharma Direct
    • Breaking News
    • Online Exclusives
    • Slideshows
    • Experts Opinions
    • Surveys
      • Outsourcing Survey
      • Salary Survey
    • Glossary
    • Videos
    • Podcasts
    • White Papers
    • Infographics
    • Contract Pharma Conference
      • Contract Pharma Conference
      • Speakers
      • Exhibitors
      • Conference Sessions
    • Supplier Microsite
      • Companies
      • News Releases
      • Posters
      • Brochures
      • Services
      • Videos
      • Case Study
      • White Papers
    • eBook
    • Webinars
    • Events
      • Industry Events
      • Live from Show Events
      • Webinars
    • Classifieds / Job Bank
      • Classifieds
      • Job Bank
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Q BioMed, Chemveda Form Cancer Collaboration

    Sign agreement for synthesis and manufacturing of liver cancer chemotherapeutic

    Related CONTENT
    • Lonza, Celltrion Sign Contract to Manufacture Remsima Drug Substance
    • Embracing Risk-Based Monitoring: The Pivotal Role of Tools and Technologies
    • CordenPharma Names New CEO
    • Penta, Cromsource Partner to Improve Pediatric Drug Development
    • 13 AstraZeneca
    09.12.19
    After the recent  successful chemical synthesis of a natural compound that has shown efficacy as a potential chemotherapy for the treatment of liver cancer, Q BioMed and Chemveda Life Sciences have formalized a collaboration to continue the work and to scale-up manufacturing of cGMP product for planned pre-clinical testing and clinical trials.
     
    Since February 2017, Q BioMed and Chemveda have been engaged in a joint research program to synthesize uttroside B and several other derivatives. The goal of the program is to study their potential use in clinical trials for the treatment of hepatocellular carcinoma (liver cancer) as well as other cancers. The original compound was isolated and characterized from the leaves of Solanum nigrum Linn, a plant widely used in traditional medicines.
     
    In a Scientific Reports study, researchers showed that in animal models, uttroside B was ten times more cytotoxic to the HepG2 liver cancer cell line than sorafenib, the only drug approved by the Food and Drug Administration for liver cancer at the time and the current first line treatment for hepatocellular carcinoma. Uttroside B drastically reduced tumors in mice bearing human liver cancer xenografts. In addition, in pre-clinical experiments, uttroside B induced cytotoxicity in all liver cancer cell lines and researchers were able to confirm its biological safety, both by in vitro and in vivo studies. Q BioMed is awaiting confirmatory cell line efficacy data from the synthesized drug product and its derivatives.
     
    “Chemveda has been an excellent partner in this program, both in terms of execution and problem solving, and we look forward to the next phase as we advance this promising molecule and others towards the clinic,” said Denis Corin, chief executive officer, Q BioMed.
     
    Bheema Paraselli, president and chief executive officer, Chemveda, said, “Since its inception in early 2017 we have been very interested in this research given to the novelty of its clinical end-point & nobility of this approach. What helped us cut through the initial uncertainty and risks surrounding the milestone approach was our stringent due-diligence, attention to detail, and tailored scientific approach. We are very thankful to Q BioMed for being of tremendous help."
    Related Searches
    • cancer
    • Manufacturing
    • Testing
    • collaboration
    Suggested For You
    Lonza, Celltrion Sign Contract to Manufacture Remsima Drug Substance Lonza, Celltrion Sign Contract to Manufacture Remsima Drug Substance
    Embracing Risk-Based Monitoring: The Pivotal Role of Tools and Technologies  Embracing Risk-Based Monitoring: The Pivotal Role of Tools and Technologies
    CordenPharma Names New CEO CordenPharma Names New CEO
    Penta, Cromsource Partner to Improve Pediatric Drug Development Penta, Cromsource Partner to Improve Pediatric Drug Development
    13	AstraZeneca 13 AstraZeneca
    SunGen Pharma, Athenex Pharma Partner for Bivalirudin Launch SunGen Pharma, Athenex Pharma Partner for Bivalirudin Launch
    Akorn Receives Warning Letter from FDA Akorn Receives Warning Letter from FDA
    Pfizer to Acquire Array BioPharma for $11.4B Pfizer to Acquire Array BioPharma for $11.4B
    Intensity Therapeutics Receives FTD for Breast Cancer Treatment Intensity Therapeutics Receives FTD for Breast Cancer Treatment
    Highlights from ASCO Highlights from ASCO
    Avadel Pharma Appoints CEO Avadel Pharma Appoints CEO
    AGC Biologics CEO to Step Down AGC Biologics CEO to Step Down
    Myoderm Announces Leadership Transition Myoderm Announces Leadership Transition
    GT Biopharma Restructures Management Team GT Biopharma Restructures Management Team
    Akorn Appoints Global Quality EVP Akorn Appoints Global Quality EVP

    Related Breaking News

    • Breaking News | Drug Development | Industry News
      Bristol Myers Squibb Expands at Cambridge Crossing

      Bristol Myers Squibb Expands at Cambridge Crossing

      Adds remaining 113,000 square feet to its initial lease at 250 Water Street.
      Kristin Brooks 04.16.21

    • Breaking News | Drug Development | Industry News
       Amgen Completes Five Prime Acquisition

      Amgen Completes Five Prime Acquisition

      Gains pipeline of immuno-oncology and targeted cancer therapies, including a Phase 3 trial-ready, first-in-class program for gastric cancer.
      Kristin Brooks 04.16.21

    • Biologics, Proteins, Vaccines | Breaking News | Industry News
      Sartorius Expands in the UK

      Sartorius Expands in the UK

      New 58,000-square-foot facility aims to simplify and accelerate the production of downstream processing equipment.
      Kristin Brooks 04.16.21


    • Capsules | Injectables | Solid Dosage/Semi-solids
      Obituary Notice: Russell “Russ” Haines

      Obituary Notice: Russell “Russ” Haines

      Former CEO of PACO Pharmaceutical Services and pharma packaging pioneer passed peacefully at the age of 93.
      Tim Wright, Editor, Contract Pharma 04.15.21

    • Bio News | Biologics, Proteins, Vaccines | Breaking News | Facilities | Industry News
      Abenza Chooses North Carolina for New Biologics Manufacturing Site

      Abenza Chooses North Carolina for New Biologics Manufacturing Site

      GMP manufacturing will commence in mid-2022.
      Charles Sternberg, Assistant Editor 04.15.21

    • Breaking News | Clinical Trial Materials | Cold Chain Management | Facilities | Industry News | Lyophilization
      Catalent Adds Cryogenic Capabilities at Philadelphia Facility

      Catalent Adds Cryogenic Capabilities at Philadelphia Facility

      Bolsters clinical supply services at site to meet growing demand for cell and gene therapy development.
      Tim Wright, Editor, Contract Pharma 04.15.21


    • Breaking News | CRO News | Industry News
      Thermo Fisher Acquires PPD for $17.4B

      Thermo Fisher Acquires PPD for $17.4B

      Further expands service offering to pharma and biotech customers.
      Tim Wright, Editor, Contract Pharma 04.15.21

    • Breaking News | Collaborations & Alliances | Industry News | Solid Dosage/Creams/Ointments
      Recro, Ensysce Expand Development and Manufacturing Partnership

      Recro, Ensysce Expand Development and Manufacturing Partnership

      Additional contract broadens and further strengthens customer product portfolio.
      Tim Wright, Editor, Contract Pharma 04.15.21

    • Breaking News | Industry News | Information Technology
      Arkema Recruits Dotmatics as its R&D Digitalization Partner

      Arkema Recruits Dotmatics as its R&D Digitalization Partner

      Agreement supports Arkema’s project to modernize access to R&D data and reduce design times for new products.
      Charles Sternberg, Assistant Editor 04.15.21


    • Breaking News | Clinical Trial Materials | Industry News | Promotions & Moves | Solid Dosage/Creams/Ointments
      Metrics Names Stephanie Emory Associate Director of Pharma Development

      Metrics Names Stephanie Emory Associate Director of Pharma Development

      Will direct team of formulation scientists who develop oral solid dose formulations for Phase I through Phase III clinical trials.
      Tim Wright, Editor, Contract Pharma 04.15.21

    • Breaking News | Drug Development | Industry News
      BioVersys Gets EIB Funds to Address Antimicrobial Resistance

      BioVersys Gets EIB Funds to Address Antimicrobial Resistance

      Financing supports development of BioVersys’ breakthrough hospital antibiotic therapy targeting Acinetobacter baumannii
      Kristin Brooks 04.14.21

    • Breaking News | Industry News | Microbiology
      Microbiologics Expands Virology Services

      Microbiologics Expands Virology Services

      Increases capabilities and capacity to provide anti-infective testing, assay development and biomaterial production services for highly infectious pathogens.
      Kristin Brooks 04.14.21


    • Biologics, Proteins, Vaccines | Breaking News | Industry News | Information Technology
      ATMPS, Ori Biotech Integrate Digital Platform for Cell & Gene Therapies

      ATMPS, Ori Biotech Integrate Digital Platform for Cell & Gene Therapies

      Aims to provide improved product tracking, scheduling and live monitoring of the manufacturing status across the entire CGT supply chain from vein to vein.
      Kristin Brooks 04.14.21

    • Breaking News | Promotions & Moves
      Executive Moves: Novavax

      Executive Moves: Novavax

      Gale Smith named SVP, Discovery and Pre-Clinical Research and Chief Scientist, and Troy Morgan named SVP, Chief Compliance Officer.
      Kristin Brooks 04.14.21

    • Biologics, Proteins, Vaccines | Breaking News | cGMP Manufacture | Industry News
      Albumedix Completes Commercial-Scale Mfg. Facility Expansion

      Albumedix Completes Commercial-Scale Mfg. Facility Expansion

      Will service increasing demand for products and technologies for cell and gene therapies, vaccines, diagnostics, protein and peptide therapeutics.
      Kristin Brooks 04.14.21

    Trending
    • Thermo Fisher Acquires PPD For $17.4B
    • Ensuring Pharma Manufacturing Quality
    • Bristol Myers Squibb Expands At Cambridge Crossing
    • Abenza Chooses North Carolina For New Biologics Manufacturing Site
    • Amgen Completes Five Prime Acquisition
    Breaking News
    • Bristol Myers Squibb Expands at Cambridge Crossing
    • Amgen Completes Five Prime Acquisition
    • Sartorius Expands in the UK
    • Obituary Notice: Russell “Russ” Haines
    • Abenza Chooses North Carolina for New Biologics Manufacturing Site
    View Breaking News >
    CURRENT ISSUE

    April 2021

    • Small Innovators & Niche CROs
    • Focus on Science
    • Rapid and Data Rich Chromatographic Method Development
    • Preparing Your Post Pandemic Talent Strategy
    • How Modern Near-Infrared Came to Be
    • Securing Your API Supply Chain: Three Keys to Success
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    AstaReal Astaxanthin Ingredient Receives U.S. Patent Approval
    Study on Kemin’s DailyZz Botanical Blend Uncovers Sleep Quality, Next-Day Performance Benefits
    FDA’s Dr. Cara Welch Opening Speaker at the 9th AHPA Botanical Congress
    Coatings World

    Latest Breaking News From Coatings World

    Jebsen & Jessen, Innospec Sign Distribution Agreement
    IGL Coatings Announces Partnership in Finland
    Axalta Schedules 1Q 2021 Earnings Conference Call
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Iterative Scopes Announces IBD-Focused Scientific Advisory Board
    Vicarious Surgical, D8 Holdings Corp. Combine Operations in $1.1 Billion Deal
    FDA Grants De Novo Clearance to Medtronic’s GI Genius Model
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Bristol Myers Squibb Expands at Cambridge Crossing
    Amgen Completes Five Prime Acquisition
    Sartorius Expands in the UK
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Former L’Oréal Exec Joins Glossier
    Lancôme Reveals New Global Sustainability Program
    First-Ever Skincare Line Focuses on Iron To Prevent Aging
    Happi

    Latest Breaking News From Happi

    Fragrance Creators Association Celebrates P&G Executive
    Evonik Highlights Solutions for Malodor Reduction
    P&G Emphasizes Small Actions at Home To Be More Sustainable
    Ink World

    Latest Breaking News From Ink World

    Kumon North America Adds Speedmaster XL 106 from Heidelberg
    SE-DA Invests in Kornit Presto S
    Acrylic Resins Market Worth $21.9 Billion by 2025: MarketsandMarkets
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    TLMI reveals Eugene Singer Award winners at Virtual Spring Summit
    Monadnock Paper Mills joins SGP
    ACTEGA helps converter reach sustainability goals
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Albaad to Add Natural-Based Line in Israel
    First Quality to Discontinue Tampon Operations
    Jessup Installs New Era Coating and Laminating Line
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    BioMagnetic Sciences Names President and CEO
    Mainstay Medical Launches ReActiv8 in Australia
    Biogennix Rolls Out Agilon Strip Bone Graft
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Virtual ASMC 2021 Spotlights Advanced Semiconductor Manufacturing Excellence
    LG Display Cuts Down CO2-eq Emissions by 3 Million Tons in 2020
    European Commission's Innovation Radar Acknowledges 3 ARMOR Innovations

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login