The three partners are cooperating closely to develop all the necessary components and manufacturing processes. This will enable customers to enter into clinical trials quicker with their drugs - often sensitive biopharmaceuticals - and commercialize them in less time. The comprehensive solution includes a ready-to-use cartriQ glass cartridge from Schott as the primary packaging for the drug, the YpsoDose patch injector platform from Ypsomed, and the processes for filling, assembly and testing of the final product by Lonza Drug Product Services (DPS). Pharmaceutical customers will thus receive a tested and documented overall solution and can concentrate on their core business.
This collaboration brings together three experts in their respective fields. All the processes and components of the solution are pre-developed, coordinated and tested. Schott develops and supplies 10ml ready-to-use cartriQ cartridges for the YpsoDose. These cartridges require fewer process steps during filling than conventional cartridges. Lonza Drug Product Services applies its expertise in process development, testing and characterization and implements a filling and assembly process for YpsoDose in Stein (Switzerland) to provide short implementation times for customers.
Andreas Reisse, Head of Schott Pharmaceutical Systems, explains, "With this new development, for which we have also made investments at our Swiss site, we are making it possible for us to jointly optimize processes for pharmaceutical companies. At the same time, we are creating completely new possibilities in the area of self-medication in terms of drug safety and user-friendliness. This is fully in line with our aim of always acting in the best possible way for the benefit of human health."
Prof. Dr. Hanns-Christian Mahler, head of Lonza Drug Product Services adds "The know-how and expertise of Lonza DPS in the development, manufacturing and testing of formulations and sterile products for subcutaneous administration is the ideal basis to enable our pharmaceutical and biotech customers to develop and commercialise the YpsoDose patch injector."
Ypsomed's platform gives customers considerable freedom in the choice of components and partners to implement their own processes as necessary. The advantage of the comprehensive solution, however, is that the three partners combine their know-how and together provide all the necessary processes and components for a short time-to-market of biopharmaceuticals.
"Together with strong partners, we offer a comprehensive solution for patch injectors so that our customers can bring their active substances and drugs to market as a commercializable product in a short time and at low cost," says Ulrike Bauer, senior vice president Delivery Systems at Ypsomed.