• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Manufacturing
    • Packaging
    • Development
    • Compliance
    • Top 25
    • Directory
    • Microsites
    • Events
    • More
  • Magazine
  • News
  • Manufacturing
  • Packaging
  • Development
  • Compliance
  • Top 25
  • Directory
  • Microsites
  • Events
  • Current / Back Issue
    Features
    Editorial
    Columns
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Subscribe Now
    Advertise Now
    Top Features
    High Drug Loading Amorphous Solid Dispersions

    Parenteral Drug Delivery Trends

    Selecting the Right Outsourcing Model for Emerging Biotech

    Inhaled Drug Delivery Technology

    The Future of Biologics: Accelerating Production, Reducing Costs
    Breaking News
    Online Exclusives
    Industry News
    Collaborations & Alliances
    Promotions & Moves
    Trials & Filings
    Financial Reports
    Bio News & Views
    Custom Sourcing News
    Packaging & Tracking
    CRO News
    Live From Shows
    Top News
    High Purity New England Bolsters Biopharma Solutions Services

    AMRI Contributes to Efforts to Increase COVID-19 Vax Supply

    CatSci Opens New Site in UK

    Pfizer Partners with Medicines Manufacturing Innovation Center

    Covectra Introduces Next-Gen Serialization Solution
    APIs
    Aseptic Processing
    Cleaning Validation
    Clinical Trial Materials
    Cytotoxics and High Potency Manufacturing
    Equipment
    Excipients
    Extractables and Leachables
    Facilities
    Fill/Finish
    Lyophilization
    Parenterals
    Process Development
    Process Validation
    Risk Management
    Scale-up/ Technology Transfer
    Solid Dosage/ Creams/ Ointments

    CatSci Opens New Site in UK

    Pfizer Partners with Medicines Manufacturing Innovation Center

    C2 Pharma Completes Multiple Regulatory Filings

    Bormioli Opens New Glass Research Center

    Why Increasing Solubility May Not Improve Bioavailability - In Vitro Predictions
    Capsules
    Cold Chain Management
    Injectables
    Logistics
    Serialization
    Solid Dosage / Semi-solids
    Supply Chain
    Vials

    Covectra Introduces Next-Gen Serialization Solution

    Bormioli Opens New Glass Research Center

    Centrient Pharmaceuticals to Acquire Astral SteriTech

    Seasonal Vaccine Manufacturing

    PwC Joins Medicines Manufacturing Innovation Centre
    Analytical Services
    Bioanalytical Services
    Bioassay Developement
    Biologics, Proteins, Vaccines
    Biosimilars
    Chemistry
    Clinical Trials
    Drug Delivery
    Drug Development
    Drug Discovery
    Formulation Development
    Information Technology
    Laboratory Testing
    Methods Development
    Microbiology
    Preclinical Outsourcing
    R&D
    Toxicology

    AMRI Contributes to Efforts to Increase COVID-19 Vax Supply

    CatSci Opens New Site in UK

    Pfizer Partners with Medicines Manufacturing Innovation Center

    CrownBio & JSR Life Sciences Partner with Cambridge Quantum Computing

    Stevanato Group Launches AI Platform
    Filtration & Purification
    GMPs/GCPs
    Inspections
    QA/QC
    Regulatory Affairs
    Validation

    The Year of COVID: How FDA Coped with a Worldwide Pandemic in 2020 and What to Expect in 2021

    Top BioPharma Form Accumulus Synergy

    Global Biosciences Co. Selects ValGenesis VLMS

    Gene Therapy Co. Selects ValGenesis' SaaS Platform

    The Year of COVID: How FDA Coped with a Worldwide Pandemic in 2020 and What to Expect in 2021
    Companies
    Categories
    Corporate Capabilities
    Add New Company
    Contract Service Directory Companies
    Adare Pharma Solutions

    Baxter BioPharma Solutions

    Syngene

    Reed-Lane

    Emergent BioSolutions
    Companies
    News Releases
    Posters
    Brochures
    Services
    Videos
    Case Study
    White Papers
    Jobs
    Contract Service Directory Companies
    Adare Pharma Solutions

    Almac Group

    Syngene

    Emergent BioSolutions

    Baxter BioPharma Solutions
    Webinars
    Live From Shows
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
      • Enewsletter Archive
      • Digital Edition
    • Directory
      • Companies
      • Categories
      • Corporate Capabilities
      • Add Your Company
    • Manufacturing
      • APIs
      • Aseptic Processing
      • Cleaning Validation
      • Clinical Trial Materials
      • Cytotoxics and High Potency Manufacturing
      • Equipment
      • Excipients
      • Extractables and Leachables
      • Facilities
      • Fill/Finish
      • Lyophilization
      • Parenterals
      • Process Development
      • Process Validation
      • Risk Management
      • Scale-up/ Technology Transfer
      • Solid Dosage/ Creams/ Ointments
      • cGMP Manufacture
    • Packaging
      • Capsules
      • Cold Chain Management
      • Injectables
      • Logistics
      • Serialization
      • Solid Dosage / Semi-solids
      • Supply Chain
      • Vials
    • Development
      • Analytical Services
      • Bioanalytical Services
      • Bioassay Developement
      • Biologics, Proteins, Vaccines
      • Biosimilars
      • Chemistry
      • Clinical Trials
      • Drug Delivery
      • Drug Development
      • Drug Discovery
      • Formulation Development
      • Information Technology
      • Laboratory Testing
      • Methods Development
      • Microbiology
      • Preclinical Outsourcing
      • R&D
      • Toxicology
    • Compliance
      • Filtration & Purification
      • GMPs/GCPs
      • Inspections
      • QA/QC
      • Regulatory Affairs
      • Validation
    • Top 25 Pharma & BioPharma
    • Contract Pharma Direct
    • Breaking News
    • Online Exclusives
    • Slideshows
    • Experts Opinions
    • Surveys
      • Outsourcing Survey
      • Salary Survey
    • Glossary
    • Videos
    • Podcasts
    • White Papers
    • Infographics
    • Contract Pharma Conference
      • Contract Pharma Conference
      • Speakers
      • Exhibitors
      • Conference Sessions
    • Supplier Microsite
      • Companies
      • News Releases
      • Posters
      • Brochures
      • Services
      • Videos
      • Case Study
      • White Papers
    • eBook
    • Webinars
    • Events
      • Industry Events
      • Live from Show Events
      • Webinars
    • Classifieds / Job Bank
      • Classifieds
      • Job Bank
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Features

    Self-Medication: Flexibility for Patients and Drug Manufacturers

    Bringing together self-medication with auto-injectors and sustainable secondary packaging.

    Self-Medication: Flexibility for Patients and Drug Manufacturers
    Image courtesy of Syntegon
    Matthias Heinrichs, Head of Product Management and Project Engineering, Syntegon Technology11.17.20
    Flexibility is the current “buzzword” in all areas of life. While everyone has a different understanding of this concept, it is definitely also finding its way into the pharmaceutical industry: patients want a better quality of life and more freedom of choice, and pharmaceutical manufacturers want to fulfill this wish with flexible equipment. In addition, the pharmaceutical industry is not immune to the current discussion evolving around sustainability. Self-medication is a good example of how these concepts can be implemented.

    To the best possible extent, advanced medical devices like auto-injectors and pen systems give patients back what they desire most: their independency, which is especially important in times of crisis as we are currently experiencing with Covid-19. Auto-injectors are already the standard equipment when it comes to medical emergencies, such as the immediate treatment of an allergic shock.

    Moreover, especially patients with chronic diseases like metabolic disorders or autoimmune diseases who require regular medication can benefit from the advances in both biopharmaceutical drug development and medical devices. Since multiple doses are needed over time for these therapies, it is easier for patients if they can self-administer the medication at home rather than having to attend several doctors’ appointments.

    Pens and auto-injectors: a growing market
    Not surprisingly, the market for auto-injectors is enjoying a period of rapid progress: according to Verified Market Research, it is projected to grow at a compound annual growth rate (CAGR) of 23.2% from 2019 to 2026. Patent expirations are further opening the market to biosimilar versions, making medication more accessible to a larger patient population. Traditional self-injection devices, such as standard syringes, are frequently being replaced by technologically advanced auto-injectors and pen systems.

    They not only help patients to improve their quality of life, pens and auto-injectors also increase patients’ adherence to their prescribed medication. What’s more, some patients who cannot use syringes due to impaired vision or dexterity can still use auto-injectors with ease. As a result of these developments, the demand for self-administrable drugs and the corresponding devices will rise even further over the coming years. At the same time, sophisticated equipment and line concepts enable pharmaceutical producers to meet the growing needs for solutions that are both flexible to manufacture and easy to administer.

    Flexible assembly and packaging
    Although many injector types have similar components, their design varies in terms of size, material and shape. Manufacturers require extremely flexible and at the same time standardized assembly platforms. This is by no means a contradiction. Machine manufacturers such as Syntegon have worked closely with customers to design the ideal mix of standardization and customization. The result: platforms such as the RDA, which are specifically configured to meet customers’ needs in terms of flexibility and capacity.

    They can assemble all known types of auto-injectors, which makes them easily adaptable to current market requirements. Moreover, they are available in both a semi-automated and a fully automated version and feature a rapid, tool-free changeover and are easy to operate. For customers such as PCI Pharma Services, the RDA makes it possible to establish a flexible assembly process with a minimum of downtime between batches, which ultimately results in cost-effective and faster production and delivery.

    Eco | Save | Pack: focus on sustainability
    Once the pens or auto-injectors have been assembled, several process steps are required before the drug can be delivered to the patient. Here, the demand for more sustainable solutions comes into play. Besides the need for more self-control in the administration of drugs, patients and the world at large are demanding more sustainability from all industries. For younger people, the look and feel as well as the quality and sustainability of packaging material of food products have become more and more important—a demand which is also growing in the pharmaceutical industry, especially but not exclusively with younger patients.

    While the majority of pens and auto-injectors will continue to be single-use devices for the obvious safety reasons, secondary packaging provides opportunities to answer the demand for resource-saving solutions. To date, pens and auto-injectors are often delivered in a combination of plastic trays or blisters, combined with folding cartons. Especially with secondary packaging, sustainability should come first, and paper packaging is the obvious choice. However, the inner lining of the secondary packaging solution is just as important—and can make a crucial difference to increasing sustainability in processes and/or packaging.

    Sustainable and easy to handle
    Recyclable materials made completely out of paper are a common market trend. Such tried and tested solutions already exist, as the example of Syntegon’s all-paper solution Eco | Save | Pack (ESP) shows. The side-loading, paper-based product inlay with a top-opening carton and glued sides protects fragile products against transport damages. A robot places the product in the inlay, where it is firmly fixed and protected. This chambered design makes sure that each pen or auto-injector is packaged in a separate chamber, thus securing it from dropping, impact and pressure during transportation and storage.

    Both the carton and the inlay of the environmentally friendly secondary packaging for fragile containers consist of mono material paper. Its high-quality look and feel further adds to an appealing product presentation. Supplements such as patient information leaflets in form of pre-folded inserts, booklets or outserts can be inserted into the packaging. The single packaging material makes the usage of a plastic tray obsolete. Consequently, no thermoforming machine is required, which in turn offers more production space, reduces costs and energy consumption. Moreover, using recyclable packaging materials also means less waste.

    For practitioners and patients, the ESP packaging is easy to handle and to open. There is no risk of getting injured at sharp edges. Removing the product from the inlay is ergonomic, while the inlay is held securely in the re-closable carton tray. The solution is available for both auto-injectors and pens in a single or multipack design.

    Right through to the patient
    Patients and their safety are the focus of drug manufacturers. Hence, they need more than a good assembly and secondary packaging system. They also need to make sure their products are safely packaged and reach the patient without being tampered with. When opting for an assembly and packaging line from Syntegon, pharmaceutical manufacturers not only receive the flexible assembly and cartoning equipment including sustainable packaging options. They also have access to serialization and aggregation solutions, as well as software solutions for data handling on the line or plant level to design a complete process from the pharmaceutical manufacturer to the patient. Especially regarding pens and auto-injectors, Syntegon has decades of experience to help establish the right process for each requirement. 


    Matthias Heinrichs is Head of Product Management and Project Engineering at Syntegon Technology, a global process and packaging technology provider. Formerly the packaging division of the Bosch Group, the company, headquartered in Waiblingen, Germany, has been offering complete solutions for the pharmaceutical and food industries for over 50 years. Fields of application in the pharmaceutical industry are the production, processing, filling, inspection and packaging of liquid and solid pharmaceuticals (e.g. syringes and capsules). Reach the author at Matthias.Heinrichs@syntegon.com or visit Syntegon online at www.syntegon.com.
    Related Searches
    • Drug Delivery

    Related Features

    • Drug Delivery
      Inhaled Drug Delivery Technology

      Inhaled Drug Delivery Technology

      The success of any new inhaled medicine relies in a large part on the correct combination of formulation and device technology being chosen for its delivery.
      Dr. Sandy Munro, Vice President – Pharmaceutical Development, Vectura 01.27.21

    • Drug Delivery
      Wet Wipes Increased Prevalence in Drug Development

      Wet Wipes Increased Prevalence in Drug Development

      A number of factors including patient preference are driving the growth of wet wipes in pharma.
      John Waddell, Business Development Director – Pharma, PDI Contract Manufacturing 10.14.20

    • Drug Delivery
      Not Your Father’s Oral Thin Film

      Not Your Father’s Oral Thin Film

      A look at how oral film drug delivery is evolving.
      Rodolphe Obeid, Vice President of Operations, IntelGenx 06.04.20


    • Drug Delivery | Regulatory Affairs
      Regulatory Overhaul for Medical Devices

      Regulatory Overhaul for Medical Devices

      Implications for the pharmaceutical industry.
      Elizma Parry, Director, Global Clinical Practice, Maetrics 06.04.20

    • Drug Delivery
      CEO Spotlight: Will Downie

      CEO Spotlight: Will Downie

      Vectura’s chief executive talks trends in the inhaled-drug market, and the company’s transition into a CDMO
      Tim Wright, Editor, Contract Pharma 04.01.20

    • Biologics, Proteins, Vaccines | Drug Delivery | Drug Development
      Knowledge Sharing: Biologics Development and Delivery

      Knowledge Sharing: Biologics Development and Delivery

      The increasing importance of sharing information to build awareness and better manage the complexities of drug development.
      Fran L. DeGrazio, Vice President of Scientific Affairs and Technical Services, West Pharmaceutical Services 09.16.19


    • Drug Delivery
      Nasal Drug Delivery

      Nasal Drug Delivery

      A look at best practices for testing nasal drug delivery devices
      Maria Smith, senior manager & Charles Shaw, scientific advisor, Renaissance Lakewood LLC 01.25.19

    • Drug Delivery | Drug Development
      Traveling Toward the Intersection of Drug Development and Delivery

      Traveling Toward the Intersection of Drug Development and Delivery

      Overcoming the challenges of delivering drugs to patients.
      Louise Righton, Global Marketing Operations Manager, 3M Drug Delivery Systems 06.12.18

    • Drug Delivery | Solid Dosage/Creams/Ointments
      FDCs on the Rise

      FDCs on the Rise

      Fixed-dose combination drugs continue to gain traction due to a multitude of benefits they offer, including speed to market a
      Betsy Louda, Associate Editor, Contract Pharma 03.09.18


    • Drug Delivery
      The Future of Inhaled Medications and Inhalation Technology

      The Future of Inhaled Medications and Inhalation Technology

      Formulations, devices and strategy through non-clinical development
      Simon Moore, Envigo 10.11.17

    • Drug Delivery
      Digital Drug Delivery: A Snapshot in Time

      Digital Drug Delivery: A Snapshot in Time

      Technology is transforming the future of drug delivery
      Sam Van Alstyne, 3M Drug Delivery Systems 10.11.17

    • Drug Delivery | Drug Development
      Two Strikes, Two Outs, or Time Out? Inhalation for Systemic Effect

      Two Strikes, Two Outs, or Time Out? Inhalation for Systemic Effect

      The challenges of using the lung as a portal for the treatment of systemic conditions
      Tugrul Kararli, Kurt Sedo, Josef Bossart, PHARMACIRCLE 10.11.16


    • Aseptic Processing | Biosimilars | Drug Delivery | Logistics | Supply Chain
      Improving Packaging Processes to Meet Regulatory and Patient Needs

      Improving Packaging Processes to Meet Regulatory and Patient Needs

      The rise of advanced automation and packaging technologies
      06.02.16

    • Biosimilars | Drug Delivery | Injectables | Parenterals | Serialization | Supply Chain | Vials
      Contract Packaging Market Trends

      Contract Packaging Market Trends

      Contract packagers talk about hot growth areas and the looming 2017 DSCSA deadline
      Tim Wright, Editor 06.02.16

    • Drug Delivery | Drug Development | Excipients | Process Development | Process Validation | Risk Management | Validation
      Process Development Trends

      Process Development Trends

      An approach to process development of pMDIs using cold fill and pressure fill technology
      Steve Haswell, 3M Drug Delivery Systems 05.05.16

    Trending
    • Catalent Acquires Delphi Genetics
    • Inside A Vaccine Trial
    • Pfizer Selects Seven Bridges To Support RNA Sequencing Data
    • Pfizer Partners With Medicines Manufacturing Innovation Center
    • ICON Acquires Medpass
    Breaking News
    • High Purity New England Bolsters Biopharma Solutions Services
    • AMRI Contributes to Efforts to Increase COVID-19 Vax Supply
    • CatSci Opens New Site in UK
    • Pfizer Partners with Medicines Manufacturing Innovation Center
    • Covectra Introduces Next-Gen Serialization Solution
    View Breaking News >
    CURRENT ISSUE

    January/February 2021

    • High Drug Loading Amorphous Solid Dispersions
    • Parenteral Drug Delivery Trends
    • Selecting the Right Outsourcing Model for Emerging Biotech
    • Inhaled Drug Delivery Technology
    • The Future of Biologics: Accelerating Production, Reducing Costs
    • Business Intelligence For (and From) the Lab
    • Communicating Your Contracting Priorities to Your Drug Company Customers
    • COVID-19 Impact Report
    • The Year of COVID: How FDA Coped with a Worldwide Pandemic in 2020 and What to Expect in 2021
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    New FDA Traceability Rule Appears to Omit Dietary Supplement Manufacturers
    Clinical Trial Finds Metabolic Benefits for Polyphenols Formula
    JRF Technology Debuts Elderberry Oral Film Strip
    Coatings World

    Latest Breaking News From Coatings World

    Universal Display Corporation, PPG Expand Global Production of UniversalPHOLED Materials
    OQ Chemicals Increases Carboxylic Acids, Esters Prices
    Sensory Analytics Announces Issuance of Broad New Patent Covering Coating Thickness Measurement
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Japan to Lead APAC Assisted Reproductive Technology Devices Market
    Portescap Slotless Brushless DC Motors Receive ISO 13485 Certification
    FDA Breakthrough Device Designation Given to MI Transcatheter Heart Pump
    Contract Pharma

    Latest Breaking News From Contract Pharma

    High Purity New England Bolsters Biopharma Solutions Services
    AMRI Contributes to Efforts to Increase COVID-19 Vax Supply
    CatSci Opens New Site in UK
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Inahsi Naturals Achieves EU Compliance
    Biden Prioritizes PPP Relief for the Beauty Industry
    Christie Brinkley Joins SBLA Beauty
    Happi

    Latest Breaking News From Happi

    Clean Beauty Collective Supports EarthDay.org
    Freckle Pens Are Spot On!
    The Detox Market Partners with Good Face Project
    Ink World

    Latest Breaking News From Ink World

    Etiflex Enters New Markets with Nilpeter FA-22 Installation
    Hydrocarbon Solvents Market to Surpass $8.1 Billion by 2030
    Lowe-Martin Adds 2 KODAK NEXFINITY Digital Presses
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    UFlex adds capacity in packaging films
    CEC expands into labels and packaging with Heidelberg
    ABG delivers Digicon Series 3 to UK printer
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Mexico City Single-Use Plastics Ban Leads to Tampon Shortage
    Believe Diapers Launch in U.S.
    Forbes Ranks Rockline Among Best U.S. Employers
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Kaia Health Unveils Next-Gen Complete MSK Care Solutions
    First Implantation of CTL Amedica's Minimally Invasive Flex Tower
    NuVasive Nabs Simplify Medical for $150M
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Comercial Kywi Improves Customer Service, Front-Store Operations with Zebra Mobile Solution
    Global Printed Circuit Board Market Projected to Reach $69.32 Billion by 2027
    RFID Locks Market to Reach $9.93 Billion by 2027: Allied Market Research

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login