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For the first time, Lilly takes the top spot with $65.2 billion in pharmaceutical sales.
June 25, 2026
By: Kristin Brooks
Managing Editor, Contract Pharma
A preview to Contract Pharma’s Guide to the Top 20 Pharma and Biopharma Companies, the following is a list of the top 10 Pharma and Biopharma companies by Pharmaceutical sales in U.S. Millions for FY2025. (excludes consumer healthcare, medical device, diagnostics division sales)
Contract Pharma’s annual guide to the 20 biggest Pharma and Biopharma players highlights key financials, top selling drugs, acquisitions and alliances, drug approvals, pipeline advances, executive moves, and more. Coming soon, Contract Pharma’s July/August Top 20 Companies Report!
LillyFY Revenues: $65,179 (+45%)Net Income: $20,640 (+95%)R&D Expenses: $13,337 (+21%)
MerckFY Revenues: $65,011 (+1%)Net Income: $18,263 (+7%)R&D Expenses: $15,789 (-12%)
RocheFY Revenues: $77,871 (+2%)Pharma Revenues: $62,598 (+3%)Net Income: $17,468 (+50%)R&D Expenses: $14,304 (-15%)
PfizerFY Revenues: $62,579 (-2%)Net Income: $7,771 (-3%)R&D Expenses: $10,437 (-4%)
AbbvieFY Revenues: $61,160 (+9%)Net Income: $ 4,226 (-1%)R&D Expenses: $9,096 (-29%)
Johnson & JohnsonFY Revenues: $94,193 (+6%)Pharma Sales $60,401 (+6%)Net Income: $26,804 (+90%)R&D Expenses: $14,665 (-15%)
AstraZenecaFY Revenues: $ 58,739 (+9%)Net Income: $10,233 (+45)R&D Expenses:14,232 (+5%)
NovartisFY Revenues: $54,532 (+8%)Net Income: $13,967 (+17%)R&D Expenses:11,200 (-12%)
SanofiFY Revenues: $51,318 (+6%)Net Income: $9,191 (+41%)R&D Expenses: $9,225 (+6%)
Novo NordiskFY Revenues: $48,680 (+6%)Net Income: $16,134 (+1%)R&D Expenses: $8,197 (+8%)
See last year’s rankings based on 2024 Pharma/Biopharma Sales
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