• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Manufacturing
    • Packaging
    • Development
    • Compliance
    • Top 25
    • Directory
    • Microsites
    • Events
    • More
  • Magazine
  • News
  • Manufacturing
  • Packaging
  • Development
  • Compliance
  • Top 25
  • Directory
  • Microsites
  • Events
  • Current / Back Issue
    Features
    Editorial
    Columns
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Subscribe Now
    Advertise Now
    Top Features
    Small Innovators & Niche CROs

    Focus on Science

    Rapid and Data Rich Chromatographic Method Development

    Preparing Your Post Pandemic Talent Strategy

    How Modern Near-Infrared Came to Be
    Breaking News
    Online Exclusives
    Industry News
    Collaborations & Alliances
    Promotions & Moves
    Trials & Filings
    Financial Reports
    Bio News & Views
    Custom Sourcing News
    Packaging & Tracking
    CRO News
    Live From Shows
    Top News
    Frontage Expands Capabilities at its Clinical Site in Secaucus, NJ

    Ascendia Pharmaceuticals Poised for Expansion

    Bora Pharmaceuticals Adds Roller Compaction Capabilities

    Merck KGaA Selects PRA’s Remote Patient Monitoring Platform

    AGC Biologics Appoints Jun Takami GM of Chiba Site
    APIs
    Aseptic Processing
    Cleaning Validation
    Clinical Trial Materials
    Cytotoxics and High Potency Manufacturing
    Equipment
    Excipients
    Extractables and Leachables
    Facilities
    Fill/Finish
    Lyophilization
    Parenterals
    Process Development
    Process Validation
    Risk Management
    Scale-up/ Technology Transfer
    Solid Dosage/ Creams/ Ointments

    Ascendia Pharmaceuticals Poised for Expansion

    Bora Pharmaceuticals Adds Roller Compaction Capabilities

    Alkermes, Merck Enter Clinical Trial and Supply Agreement

    Sterling Pharma Solutions Acquires ADC Biotechnology

    Moderna, Catalent Enter Long-Term Strategic Vax Pact
    Capsules
    Cold Chain Management
    Injectables
    Logistics
    Serialization
    Solid Dosage / Semi-solids
    Supply Chain
    Vials

    Cryoport Acquires Critical Transport Solutions Australia

    PharmParts – This Makes Sense!

    Securing Your API Supply Chain: Three Keys to Success

    Enteris BioPharma: Custom Solutions – From Bench to Market

    The Benefits of Outsourcing Cold Storage
    Analytical Services
    Bioanalytical Services
    Bioassay Developement
    Biologics, Proteins, Vaccines
    Biosimilars
    Chemistry
    Clinical Trials
    Drug Delivery
    Drug Development
    Drug Discovery
    Formulation Development
    Information Technology
    Laboratory Testing
    Methods Development
    Microbiology
    Preclinical Outsourcing
    R&D
    Toxicology

    Frontage Expands Capabilities at its Clinical Site in Secaucus, NJ

    Ascendia Pharmaceuticals Poised for Expansion

    Merck KGaA Selects PRA’s Remote Patient Monitoring Platform

    Agilex Biolabs Acquires TetraQ for APAC Expansion Plans

    Alkermes, Merck Enter Clinical Trial and Supply Agreement
    Filtration & Purification
    GMPs/GCPs
    Inspections
    QA/QC
    Regulatory Affairs
    Validation

    What Will Change at FDA for 2021?

    RBQM Comes of Age: COVID as a Catalyst for Change

    Post-Pandemic Regulations

    Enteris BioPharma: Custom Solutions – From Bench to Market

    Metrics Contract Services Completes Russian Regulatory Inspection
    Companies
    Categories
    Corporate Capabilities
    Add New Company
    Contract Service Directory Companies
    Adare Pharma Solutions

    Reed-Lane

    Baxter BioPharma Solutions

    Syngene

    Aphena Pharma Solutions
    Companies
    News Releases
    Posters
    Brochures
    Services
    Videos
    Case Study
    White Papers
    Jobs
    Contract Service Directory Companies
    Emergent BioSolutions

    Syngene

    Almac Group

    Reed-Lane

    Adare Pharma Solutions
    Webinars
    Live From Shows
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
      • Enewsletter Archive
      • Digital Edition
    • Directory
      • Companies
      • Categories
      • Corporate Capabilities
      • Add Your Company
    • Manufacturing
      • APIs
      • Aseptic Processing
      • Cleaning Validation
      • Clinical Trial Materials
      • Cytotoxics and High Potency Manufacturing
      • Equipment
      • Excipients
      • Extractables and Leachables
      • Facilities
      • Fill/Finish
      • Lyophilization
      • Parenterals
      • Process Development
      • Process Validation
      • Risk Management
      • Scale-up/ Technology Transfer
      • Solid Dosage/ Creams/ Ointments
      • cGMP Manufacture
    • Packaging
      • Capsules
      • Cold Chain Management
      • Injectables
      • Logistics
      • Serialization
      • Solid Dosage / Semi-solids
      • Supply Chain
      • Vials
    • Development
      • Analytical Services
      • Bioanalytical Services
      • Bioassay Developement
      • Biologics, Proteins, Vaccines
      • Biosimilars
      • Chemistry
      • Clinical Trials
      • Drug Delivery
      • Drug Development
      • Drug Discovery
      • Formulation Development
      • Information Technology
      • Laboratory Testing
      • Methods Development
      • Microbiology
      • Preclinical Outsourcing
      • R&D
      • Toxicology
    • Compliance
      • Filtration & Purification
      • GMPs/GCPs
      • Inspections
      • QA/QC
      • Regulatory Affairs
      • Validation
    • Top 25 Pharma & BioPharma
    • Contract Pharma Direct
    • Breaking News
    • Online Exclusives
    • Slideshows
    • Experts Opinions
    • Surveys
      • Outsourcing Survey
      • Salary Survey
    • Glossary
    • Videos
    • Podcasts
    • White Papers
    • Infographics
    • Contract Pharma Conference
      • Contract Pharma Conference
      • Speakers
      • Exhibitors
      • Conference Sessions
    • Supplier Microsite
      • Companies
      • News Releases
      • Posters
      • Brochures
      • Services
      • Videos
      • Case Study
      • White Papers
    • eBook
    • Webinars
    • Events
      • Industry Events
      • Live from Show Events
      • Webinars
    • Classifieds / Job Bank
      • Classifieds
      • Job Bank
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Pharma Beat

    Could Nuts Ward Off Cancer?

    Recent research looks into the anti-cancer properties of various nuts

    Related CONTENT
    • BMS, Calithera Biosciences Expand Clinical Collaboration
    • Tackling TB Resistance
    • Takeda Inks $100M Pact With GammaDelta
    • Regeneron, SillaJen in Clinical and Supply Pact
    • Plasticell, Kings College Partner on Blood Platelet Substitute    
    Adele Graham-King, Contributing Editor04.03.17
    As kids we’re warned of the dangers of nuts due to allergies and anaphylactic shock. As adults we’re warned that they’re high in fat content and can contain high amounts of salt. However, recent studies in the UK and other countries have suggested that giving young children small amounts of peanut products can reduce the incidence of allergies developing in childhood drastically.

    One study published by Kings College Researchers in 2015 suggested that babies who were exposed to small amounts of peanut-based foods showed an 86% reduction in allergy development prior to the age of 5 (14% compared to 2% following exposure). Now, there’s mounting evidence to suggest that eating small amounts of nuts daily can reduce the risk of developing various types of cancer.

    In itself, the anti-malignancy effect of nuts isn’t completely new. However, there is mounting evidence that could change the way we think about nuts.

    Walnuts and Brazil nuts seem to have generated particular interest with regards to their cancer defending capabilities. Noted on the American Institute for Cancer Research (AICR) website, walnuts are distinctly recognized as being the most studied nut for cancer prevention. They contain various chemicals in higher quantities than other nuts such as polyphenols and phytochemical, which have proven antioxidant properties. They are high in ellagitannins (ellagic acid), which have been studied for their positive effect on various tumor types including breast, pancreas, skin, colon and prostate. They also have a wealth of other compounds such as Gamma-tocopherol (Vitamin E type), Alpha-linolenic acid (Omega-3 fatty acid), phytosterols and melatonin.

    Brazil nuts differ in that they have high amounts of selenium, an antioxidant trace mineral, which has well-recognized health benefits. A small handful of these little gems can contain as much as 480% GDA of selenium, and surprisingly there is plenty of evidence to support the anti-cancer activity of the element, particularly with regards to prostate cancer. Evidence presented in the Journal of the American Medical Association (JAMA) in the late 90s reported that long-term dietary supplementation of selenium can deliver a strong reduction in cancer mortality across a wide range of tumors, however specifically within prostate cancer this was suggested to be as high as 42%. Walnuts have also been investigated in mouse-based breast cancer models which have reflected similar results to the prostate cancer study.

    You can see that, heading upwards of 40 years, researchers, dieticians and alternative therapists, have been praising the health benefits of nuts and their place in a healthy diet. We’ve highlighted only two types but the suggested benefits extend to many varieties. Although it’s possible to attribute many of these health benefits to many of the chemical compounds that are found in nuts, it’s not clear how the anti-carcinogenic protective mechanisms function at a deeper cellular level.

    The good news is that this information has potentially been uncovered. Researchers based in the Department of Nutritional Toxicology at the University of Jena (Germany) have recently reported the outcomes of their work into the onco-protective activity of various types of nuts.

    Working on the basis that nuts seem to have demonstrated the ability to reduce the incidence of certain types of colon cancer, the investigators, led by Dr. Wiebke Schlörmann, gained insights into the chemo-preventative effects of five different varieties of nuts including macadamia nuts, hazelnuts, almonds, pistachios and walnuts. Using a process of fermentation, the nuts were artificially digested in test tubes and the resulting metabolites applied to colon adenoma and primary epithelial colon cell lines.
    The outcomes suggested a surprise ability of the nut ferment to disable and detoxify harmful oxidative cancer inducing cells. It seems that the nuts are able to activate our bodies own defenses by increasing the activity of the protective enzymes catalase and superoxide dismutase. Furthermore, they exhibited the ability to initiate apoptosis (programmed cell death) in the colon cancer cells. It seems that the effect takes place at a genetic level as specific types of mRNA were significantly enhanced as well as modulation of other genes, which play a pivotal part in the detoxification cycle and cell proliferation. The multi-pronged attack on the cancer cells has created new insight into the induced activity of nuts at a cellular level.

    Published in the journal Molecular Carcinogenesis in February 2017 the article suggests that these effects were exhibited by all types of nuts to a similar extent in colon cancer cells. The research team now plans to compare the effect of roast nuts with that of uncooked ones. As most nuts are sold and consumed after roasting, this has the potential to allow appropriate dietary advice for the best health benefits.


    Adele Graham-King
    Contributing Editor

    Adele is a design consultant who works in product development for medical and healthcare applications. Her background is in pharma, and she has a degree in applied physiology.
    Related Searches
    • Pharma
    • Development
    • brazil
    • cancer
    Suggested For You
    BMS, Calithera Biosciences Expand Clinical Collaboration BMS, Calithera Biosciences Expand Clinical Collaboration
    Tackling TB Resistance Tackling TB Resistance
    Takeda Inks $100M Pact With GammaDelta Takeda Inks $100M Pact With GammaDelta
    Regeneron, SillaJen in Clinical and Supply Pact Regeneron, SillaJen in Clinical and Supply Pact
    Plasticell, Kings College Partner on Blood Platelet Substitute     Plasticell, Kings College Partner on Blood Platelet Substitute    
    Every Voice Every Voice
    Parker domnick hunter Expands European Ops Parker domnick hunter Expands European Ops
    AbbVie Joins ORIEN Research Exchange AbbVie Joins ORIEN Research Exchange
    Vedantra Forms Research Collaboration with Neon Therapeutics Vedantra Forms Research Collaboration with Neon Therapeutics
    The Trials and Tribulations  of Male Contraception The Trials and Tribulations of Male Contraception
    Precision Medicine Precision Medicine
    GW Pharmaceuticals Appoints CFO, Adds UK Director GW Pharmaceuticals Appoints CFO, Adds UK Director
    BMS, GRAIL in Precision Medicine Pact BMS, GRAIL in Precision Medicine Pact
    Sanofi Appoints UK GM and Medical Chair Sanofi Appoints UK GM and Medical Chair
    ‘Smart’ Heparin Delivery Could Self-Modulate ‘Smart’ Heparin Delivery Could Self-Modulate

    Related Pharma Beat

    • Drug Development

      NSAIDs – Friend or Foe?

      Although widely used for years, NSAIDs have side effects that could eventually change their OTC status
      Adele Graham-King, Contributing Editor 06.06.17

    • Drug Development | Drug Discovery
      Tackling TB Resistance

      Tackling TB Resistance

      The TB Alliance is partnering with universities, government agencies, public agencies and a small number of pharma compani
      Adele Graham-King, Contributing Editor 05.09.17

    • Drug Delivery | Drug Development | R&D

      ‘Smart’ Heparin Delivery Could Self-Modulate

      A group of researchers have spent the past two years investigating self-controlling dosing and monitoring systems
      Adele Graham-King, Contributing Editor 01.26.17


    • Drug Development | Drug Discovery | R&D

      Is Nicotine Such a ‘Bad Boy’?

      Investigating this controversial compound’s potential health benefits
      Adele Graham-King, Contributing Editor 11.09.16

    • Drug Development | Drug Discovery | R&D

      Blackberry Wine: Could it Help Your Diabetes?

      Recent research points towards the positive impact ‘berry wine’ might have on diabetes
      Adele Graham-King, Contributing Editor 10.11.16

    • Chemistry | Drug Development
      Anyone Fancy a Beer?

      Anyone Fancy a Beer?

      The centuries-old brew continues to be investigated for its medicinal properties
      Adele Graham-King, Contributing Editor 05.05.16


    • Drug Development

      Chipping Away at the Old Cancer Block

      Advances in cancer treatment continue to march towards finding a cure
      Adele Graham-King, Contributing Editor 04.05.16

    • Clinical Trials | Drug Development

      The 3D Printed Pill

      It’s the future…or is it?
      Adele Graham-King, Contributing Editor 01.28.16

    • Clinical Trials | Drug Development | Drug Discovery | R&D

      Are We There Yet?

      Many promising cancer treatments are on the horizon
      Adele Graham-King, Contributing Editor 07.14.15


    • APIs | Bioassay Development | Drug Development | Methods Development | Process Development | Toxicology

      The Last Chance Saloon?

      Looking at the pharmaceutical ‘diet’ of anti-obesity drugs
      Adele Graham-King, Contributing Editor 06.02.15

    • Clinical Trials | Drug Development

      100 New Drugs in 10 Years?

      Repurposing drug candidates that never saw the light of day
      Adele Graham-King, Contributing Editor 03.06.15

    • APIs | Bioassay Development | Clinical Trials | Drug Development | Drug Discovery | Methods Development | Process Development | R&D | Toxicology

      Experimental Drugs

      To use or not to use unlicensed drugs? That is the question.
      Adele Graham-King, Contributing Editor 01.29.15


    • Drug Delivery | Drug Development
      The End of a Century

      The End of a Century

      Looking at 15 years of pharmaceutical evolution.
      Adele Graham-King 10.14.14

    • Bioassay Development | Drug Development | Methods Development | Process Development | Toxicology

      A Questionable Combination

      ...
      Ed Silverman, Contributing Editor 06.05.13

    • Drug Development | R&D

      The Long Pharm of the Law

      Will FDA pursue criminal charges for execs in pharma cases?
      Ed Silverman 04.05.10

    Trending
    • Sterling Pharma Solutions Acquires ADC Biotechnology
    • Ascendia Pharmaceuticals Poised For Expansion
    • Sanofi To Build New $700M Flu Vaccine Facility In Canada
    • Frontage Expands Capabilities At Its Clinical Site In Secaucus, NJ
    • Merck KGaA Selects PRA’s Remote Patient Monitoring Platform
    Breaking News
    • Bora Pharmaceuticals Adds Roller Compaction Capabilities
    • Ascendia Pharmaceuticals Poised for Expansion
    • Frontage Expands Capabilities at its Clinical Site in Secaucus, NJ
    • Merck KGaA Selects PRA’s Remote Patient Monitoring Platform
    • AGC Biologics Appoints Jun Takami GM of Chiba Site
    View Breaking News >
    CURRENT ISSUE

    April 2021

    • Small Innovators & Niche CROs
    • Focus on Science
    • Rapid and Data Rich Chromatographic Method Development
    • Preparing Your Post Pandemic Talent Strategy
    • How Modern Near-Infrared Came to Be
    • Securing Your API Supply Chain: Three Keys to Success
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Kyowa Hakko Launches Heat-Treated Probiotic Strain for Eye Health
    CGA-7 Green Coffee Extract by Vidya Herbs Achieves Self-Affirmed GRAS Status
    Nutritional Complex Evidenced to Reduce Preterm Birth
    Coatings World

    Latest Breaking News From Coatings World

    Chromaflo Technologies to Sponsor and Exhibit at the North American Pultrusion Conference 2021
    Barentz Expands Canadian CASE Team
    Shepherd Color Company Opens Sales Office in China
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    CMS Establishes New Payment for Pelvalon’s Eclipse System
    Varian, Google Cloud Partner to Bring Convenience to Cancer Therapy
    Resonetics Leases New Manufacturing Space in Costa Rica
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Frontage Expands Capabilities at its Clinical Site in Secaucus, NJ
    Ascendia Pharmaceuticals Poised for Expansion
    Bora Pharmaceuticals Adds Roller Compaction Capabilities
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Revlon Unveils New Fragrances Featuring Megan Thee Stallion & Sofia Carson
    Henkel Management Board Welcomes Wolfgang König
    Mielle Organics Gets a Major Investment
    Happi

    Latest Breaking News From Happi

    Nature’s Beauty Debuts Vegan Natural Body Care at Walgreens
    Estée Lauder Expands Beautiful Fragrance Collection
    The Honest Company Files for IPO
    Ink World

    Latest Breaking News From Ink World

    SE-DA Invests in Kornit Presto S
    Kumon North America Adds Speedmaster XL 106 from Heidelberg
    Iron Oxide Pigments Market to Register 4.7% CAGR from 2021 to 2028: GVR
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Dantex elevates Joseph Sanchez to digital business development manager
    Mactac's Kevin Clunie joins TLMI panel
    MacDermid announces two new global sales roles
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Precision Textiles Offers Biodegradable Medical Fabric
    Northshore Launches Megamax Briefs in New Colors
    Essity Acquires Distribution Rights to Sorbact in Australia and New Zealand
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    New Biosealant Could Stabilize Cartilage, Boost Healing After Injury
    Google Executive Joins SeaSpine's Board of Directors
    HSS and LimaCorporate Open Provider-Based 3D Design and Printing Facility
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Tive Multi-sensor Tracker Solo 5G Relies on Sensirion SHT33
    VTT in 2020: Successful Year Despite Globally Challenging Times
    Lux Research: 3D Printing Market to Reach $51 Billion in 2030

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login