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Technical considerations for selecting your next oral dosage form.
Released By Douglas CDMO
September 3, 2024
Formulating active pharmaceutical ingredients (APIs) often presents significant challenges, such as instability, low solubility, low permeability and potential safety concerns. The properties of softgel products, including their oil-based nature to improve drug absorption and sealed environment to reduce dust and operator exposure, help to overcome these issues. Softgel capsules are highly versatile, capable of encapsulating a wide range of APIs in various forms, including solutions, suspensions, and semi-solids. They have played a crucial role in the success of many drugs by addressing stability and shelf-life challenges, while offering significant advantages that enhance drug delivery and patient compliance. Chris Cuthbertson, Program Manager of Pharmaceutical Development at Douglas CDMO, explores the technical aspects of softgel formulations and explains why their unique characteristics make them a preferred dosage form for manufacturers and patients alike.
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