Services

Sterile Injectable Fill/Finish

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Released By Jubilant HollisterStier CMO

Jubilant HollisterStier offers 4 high speed commercial vial filling lines that include:

  • Fully integrated lines
  • Aseptic compounding
  • Diaphragm pump technology
  • Terminal sterilization capabilities
  • Oxygen reduction system
  • 2mL to 100 mL vials
  • Also, ampoule fillers


Commercial Sterile Filling- Spokane facility

Jubilant HollisterStier’s Spokane Washington, USA, facility offers two parenteral manufacturing complexes capable of aseptically filling liquid and lyophilized products. Two commercial high-speed lines able to aseptically fill liquid and lyophilized pharmaceutical products.  

Our Spokane facility can accommodate vials from 2mL through 100mL, and batch sizes from 2 to 1,500 liters. 

  • Vials from 2mL through 100mL
  • ISO5 oversealing environment
Commercial Lyophilization- Spokane facility
  • 1,200 combined ft2 of shelf space
  • Automatic CIP and SIP
  • Automatic vial load/unload
  • -45°C cold shelf loading
  • Clinical to commercial sized batches
  • 385 ft2,  220 ft2 and 30 ft2 chambers
Vial size Quantity (max per batch for 385 ft2 lyos)
2mL 153,000
3mL 114,000
10mL 82,000
30mL 36,000
100mL  14,000


Commercial Sterile Filling- Montreal facility

Our Montreal facility offers the following sterile injectable capabilities:
  • Four sterile filling suites for quick change-overs and flexibility
  • Fully automated CIP / SIP
  • Aseptic filling and terminal sterilization vials from 2mL to 40 mL
STERILE DOSAGE FORM FORMAT 
Injectables ampoules, vials 

  
Commerical Lyophilization- Montreal facility
   
The lyophilization suite at our Montreal facility is integrated into our high speed filling line. Robotic loading systems results in accelerated freezing time, minimized product degradation and reduced risk of microbial contamination.

  • Two BOC/Edwards lyophilizers with production capacity of 374 ft2 of freeze-drying shelf space (120 and 254 ft2)
  • Semi-automated inspection of vials for quality assurance
Ampoule filling lines include:
  • Rota Filler
  • aseptic filling
  • terminal sterilization
  • heat and light sensitive products
  • 1 mL to 10 mL ampoules
  • automatic particle and pinhole inspection (EISAI)

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