Beyond the Capsule: Unlocking the Full Potential of Lipid Excipients in Oral Solid Dosage Forms

Lipid excipients offer significant in vivo performance benefits for oral drug delivery by improving solubility/bioavailability, enhancing absorption, and mitigating food effect. While lipids have found commercial success in soft gel capsules and liquid-filled hard capsules, there is growing interest in incorporating the benefits of lipid excipients into oral solid dosage forms, such as tablets.

This presentation will highlight emerging research and formulation strategies that expand the use of lipid excipients in oral tablet development. 

Key topics will include:

• • In vivo benefits of lipid excipients for solubility and permeability.
• • Combining lipids with polymers to optimize oral tablet performance.
• • Incorporating lipids into tablets via common processing techniques.
• • Case studies showcasing lipid-enabled tablet formulations.