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List Bio Raises $48.4M for Global Scale-Up

Plans to build a large-scale manufacturing facility in Fishers, Indiana.

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By: Tim Wright

Editor-in-Chief, Contract Pharma

List Biotherapeutics has unveiled plans for a new manufacturing facility in the Fishers Life Science & Innovation Park, Indiana after closing their Series A round investment.

List Bio is the latest venture of Genome and Company, a global provider of microbiome anticancer drug development, which has expanded into the U.S. in the last 18 months with a majority strategic investment in List Labs and Scioto Biosciences located in Campbell, CA and Fishers, IN.

The new company raised a $31 million tranche of Series A financing last December followed by a second tranche of $17.4 million in March 2022.

With the Series A investment, List Bio plans to establish a manufacturing facility in the Fishers Life Science & Innovation Park in Fishers, Indiana. Upon completion, List Bio, together with List Labs, the first CDMO to produce a live biotherapeutic product (LBP) for clinical trial, will offer an end-to-end manufacturing solution for early-stage development through commercial production of new microbiome therapeutics.

The collaboration with List Labs will build on 40 plus years of bacterial strain experience and expertise and support a microbiome therapeutics market that research firm MarketsandMarkets expects to grow at a CAGR of 21.5%, from $788.8 million in 2025, to $1.416 billion in 2028.

The 110,000 square foot contract manufacturing facility will create hundreds of new jobs in the city of Fishers. 

“I am grateful to the investors who believed in the growth potential of our microbiome CDMO business,” said Jisoo Pae, founder and CEO of Genome and Company. “We will develop new microbiome therapeutics and kick-start the new business as part of our aim to lead the way as the distinguishing microbiome biotech with a fully integrated pharmaceutical value chain.”

The company’s decision to build in Fishers was driven by its status as a destination for technology and life science industry growth. The Fishers Life Science & Innovation Park was established in August 2021 and has seen more than $200 million in investment from life science firms Stevanato Group and INCOG Pharma. List Bio will contribute a further $125 million with the List Bio investment, in addition to the $10.5 million already invested into Fishers-based Scioto Biosciences.

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