Servier Agrees to Acquire Muscular Dystrophy Business of Edgewise Therapeutics

Servier, an independent international pharmaceutical group governed by a foundation, has entered into an agreement to acquire the muscular dystrophy business of Edgewise Therapeutics Inc., a biopharmaceutical company focused on developing innovative therapies for serious muscle disorders, for up to $2.65 billion, including upfront payment of $1.55 billion as well as up to $1.1 billion in regulatory and commercial milestone payments.

The transaction has been approved by both companies’ respective governance bodies. The transaction is subject to regulatory clearance and customary closing conditions and is expected to close in the third quarter of 2026. This acquisition follows Servier’s acquisition of Day One Biopharmaceuticals earlier this year.

This acquisition of Edgewise Therapeutics’ muscular dystrophy business includes its associated capabilities as well as sevasemten, an investigational orally administered first-in-class fast skeletal myosin inhibitor designed to preserve and protect unstable muscle against contraction-induced damage in individuals living with rare muscular dystrophy. Sevasemten is currently investigated in a pivotal cohort in Becker muscular dystrophy (BMD), and in phase 2 in Duchenne muscular dystrophy (DMD). This drug candidate has the potential to position Servier as a global player with strong capabilities and a pipeline in neuromuscular disorders. 

“The acquisition of Edgewise Therapeutics’ muscular dystrophy business is a key step forward to achieve our Servier 2030 ambition in neurology with a team of talented experts and a promising asset in muscular dystrophies,” said Olivier Laureau, President of Servier. “This acquisition aims to provide targeted therapies to patients with rare neuromuscular disorders. Developing treatments for young and adult patients, with highly debilitating rare conditions and limited to no options today, is at the heart of our mission.”

“We believe Servier is well positioned to advance sevasemten and the muscular dystrophy program given its commitment to patients, growing focus in neurology, and global development capabilities,” said Kevin Koch, Ph.D., President and CEO of Edgewise Therapeutics. “This transaction is designed to place the program in the hands of an organization with the experience and infrastructure to support its continued development for people living with Becker and Duchenne muscular dystrophies.”

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