Evotec Makes Continuous Manufacturing Technology Available on a Turnkey Basis

Editor’s Take: Demand for continuous manufacturing continues to grow. Learn about its advantages over batch manufacturing.

Evotec SE has expanded its Just – Evotec Biologics services with J.TRAIN, a new offering that enables biopharmaceutical companies to deploy Evotec’s proprietary continuous manufacturing technology directly within their own facilities on a turnkey basis.

J.TRAIN brings together prefabricated modular cleanrooms and industry-standard manufacturing equipment with Just – Evotec Biologics’ cGMP-compliant process automation, designed to enable significantly faster and more cost-effective deployment than traditional manufacturing expansion.

Linda Zuckerman, PhD, EVP Global Head of Just – Evotec Biologics, said, “J.TRAIN is a disruptive opportunity for industry to increase capacity and manufacture biologics at reduced costs and improved productivity, with deployment in as little as 18 months. It exemplifies the strategic shift in Just – Evotec Biologics toward a rapidly deployable, capital-lighter and technology-focused business model.”

According to Zuckerman, the company now combines technology licensing with process design and engineering capabilities, “enabling the fast establishment and implementation of the most advanced continuous manufacturing processes, giving companies greater, tunable control over clinical and commercial materials.”

The model was validated by its December 2025 transaction with Sandoz, which included the provision of a manufacturing facility alongside a license to Just – Evotec Biologics’ proprietary manufacturing technology, demonstrating both its feasibility and scalability.”

J.TRAIN can enable the production of more than 500 kilograms of drug substance from less than 10,000 square feet of cleanroom space, achieving productivity levels more than ten times traditional methods. This efficiency is expected to translate into substantially lower operating costs per unit mass while allowing production scale to be flexibly adjusted through the duration of manufacturing runs rather than the size of the facility. Furthermore, the integrated nature of the J.TRAIN design allows for rapid transitions between products, minimizing downtime and supporting multi-product manufacturing environments.