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Highlights several drug-delivery system and packaging component technologies
October 4, 2016
By: Tim Wright
Editor-in-Chief, Contract Pharma
West Pharmaceutical Services is sharing its packaging and drug-delivery solutions for the bio/pharmaceutical industry at this year’s CPhI. According to Mike Schaefers, vice president, global product management and marketing operations at West, sophisticated biologic drug products for the treatment of chronic diseases are becoming more prevalent, and there is a demand for integrated containment and delivery systems designed to accommodate these highly sensitive molecules. West is showcasing several drug-delivery system and packaging component technologies, including: • 1–3mL NovaPure plungers for higher-volume prefilled delivery systems, designed using quality-by-design (QbD) principles to reduce particulate and ensure consistency of delivery. • SmartDose technology platform, which is used in Amgen’s single, monthly 420 mg dose delivery option for Repatha (evolocumab), recently approved by FDA. This is the first combination product that incorporates SmartDose technology for use in the U.S. • Daikyo Crystal Zenith vials and 1-mL long insert needle syringes are containment systems manufactured from a cyclic olefin polymer that offer a break-resistant, high-performance alternative to glass for complex drugs. • Daikyo RUV components are ready-to-use, validated components manufactured using clean, high-quality elastomer formulations and then washed, camera-inspected, and sterilized to help minimize risks around component preparation and eliminate bioburden. At CPhI InnoPack, West will present the following educational session Oct. 5, 11 a.m.: “Lifecycle management and continuous improvement efforts on components to address steadily increasing patient and quality expectations,” Christa Jansen-Otten, director, product management, prefillable solutions and delivery, West.
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