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Helps solve formulation and scale-up challenges.
September 18, 2020
By: Contract Pharma
Contract Pharma Staff
The Diosna Dierks & Söhne GmbH recently opened the “Diosna ProcessLab” located in Osnabrück, Germany. The lab, which was completed in April 2020, offers research and formulation trials as well as virtual and in-person training classes. It offers an overview of the different system options and various possibilities for experimental implementation. The NP-RD30 Rotary Tablet Press One of the systems included in the Diosna ProcessLab is the Natoli NP-RD30, which is designed to help solve formulation and scale-up challenges. The multi-functional rotary tablet press replicates the design and functionality of a full-scale production press with the analytical capabilities of an R&D machine. The NP-RD30 helps to get products to market faster with the data acquisition, analysis, and scalability features included in its user-friendly interface. The NP-RD30 is 21 CFR Part 11 compliant. It comes with an intuitive 21” HMI touchscreen and USB port for data transfer. Rolling casters allow for easy mobility of the machine. The NP-RD30 is equipped with an integrated duel vacuum system, a built-in calibration tool, upper and lower punch seals, powder recirculation system, and self-adjusting lower punch retainers with an exclusive push button feature. Efficient and Dependable An optimized fast-fill cam design creates a vacuum to assist in die filling for more consistent tablet weights. The NP-RD30 is designed with same diameter pre- and main compression rollers, independent overload, ejection, and take-off force monitoring. While designed to meet the needs of research and development, the NP-RD30 can also be used as a small batch production press with efficient and dependable standard batch reporting. The NP-RD30 will be used to help enable the complete production of tablets for seminars, training, and more. The tablet press completes the manufacturing process chain at the Diosna ProcessLab that starts with powder mixing, granulation, final blending, tableting (completed with the NP-RD30), and finally, coating of the tablets. Customers who perform formulation trials at Diosna ProcessLab, are able to compress the granules to tablets, getting the opportunity to handle and analyze the quality of the final tablet with all its physical and chemical characteristics. The first seminar in the new Diosna ProcessLab, “PTS-Seminar: Intensive Training Wet Granulation,” is planned for October 28-29, 2020 depending on availability of the Diosna ProcessLab due to current global circumstances. The number of attendees has been reduced to provide a safe environment in accordance with the Good Manufacturing Practice (GMP) standards with the World Health Organization (WHO). The Diosna ProcessLab and the equipment was also built according to GMP standards.
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