Contract Pharma Staff10.06.20
Evonik has launched an advanced oral drug delivery technology that provides enteric protection followed by rapid, homogeneous release for effective targeting of the upper small intestine.
According to the company, EUDRATEC Fasteric releases on average 90% of its dose within 30 minutes of arrival at a pre-defined pH level between 3.0 and 5.5. The proprietary delivery technology can increase gastric resistance and improve intestinal absorption for oral drug products that target sites in the upper small intestine where there is a narrow absorption window. It is also fast and easy to process using standard equipment, and suitable for use with a range of oral dosage forms including multiparticulates, tablets and capsules.
“Many APIs are best absorbed through the proximal part of the small intestine,” said Paul Spencer, head of pharma polymers and services at Evonik. “Enteric protection, followed by early, fast and homogeneous release at the right pH level, can be essential to maximize absorption and enhance bioavailability. With the launch of EUDRATEC Fasteric, Evonik has addressed another major unmet need for oral drug delivery.”
Evonik’s broad portfolio of EUDRAGIT functional coatings and advanced drug delivery technologies can effectively target virtually any gastrointestinal site.
“EUDRATEC Fasteric is ideal for the precise targeting of sites such as the duodenum where there is a narrow absorption window,” said Jessica Mueller-Albers, director strategic marketing oral drug delivery solutions at Evonik. “Other technologies within our portfolio such as DuoCoat, Phloral and EUDRATEC COL enable high-precision targeting for the ileocolonic region. The versatility of our portfolio and extensive formulation expertise means we can reliably help pharmaceutical customers address their specific release profile requirements. Being able to offer such a broad range of absorption solutions for targeting throughout the gastrointestinal tract makes Evonik an attractive partner for the development of delayed release oral solid dosage forms.”
Evonik’s Health Care business line is one of the world’s leading pharmaceutical partners for advanced drug delivery. Being part of the Nutrition and Care division of Evonik, it provides pharmaceutical and biotechnology companies with a unique, integrated portfolio of functional excipients, delivery technologies and CDMO services for complex oral and parenteral dosage forms. It is also one of the world’s largest suppliers of generic APIs, amino acids and cell culture ingredients, and a top three global CMO for APIs and intermediates.
According to the company, EUDRATEC Fasteric releases on average 90% of its dose within 30 minutes of arrival at a pre-defined pH level between 3.0 and 5.5. The proprietary delivery technology can increase gastric resistance and improve intestinal absorption for oral drug products that target sites in the upper small intestine where there is a narrow absorption window. It is also fast and easy to process using standard equipment, and suitable for use with a range of oral dosage forms including multiparticulates, tablets and capsules.
“Many APIs are best absorbed through the proximal part of the small intestine,” said Paul Spencer, head of pharma polymers and services at Evonik. “Enteric protection, followed by early, fast and homogeneous release at the right pH level, can be essential to maximize absorption and enhance bioavailability. With the launch of EUDRATEC Fasteric, Evonik has addressed another major unmet need for oral drug delivery.”
Evonik’s broad portfolio of EUDRAGIT functional coatings and advanced drug delivery technologies can effectively target virtually any gastrointestinal site.
“EUDRATEC Fasteric is ideal for the precise targeting of sites such as the duodenum where there is a narrow absorption window,” said Jessica Mueller-Albers, director strategic marketing oral drug delivery solutions at Evonik. “Other technologies within our portfolio such as DuoCoat, Phloral and EUDRATEC COL enable high-precision targeting for the ileocolonic region. The versatility of our portfolio and extensive formulation expertise means we can reliably help pharmaceutical customers address their specific release profile requirements. Being able to offer such a broad range of absorption solutions for targeting throughout the gastrointestinal tract makes Evonik an attractive partner for the development of delayed release oral solid dosage forms.”
Evonik’s Health Care business line is one of the world’s leading pharmaceutical partners for advanced drug delivery. Being part of the Nutrition and Care division of Evonik, it provides pharmaceutical and biotechnology companies with a unique, integrated portfolio of functional excipients, delivery technologies and CDMO services for complex oral and parenteral dosage forms. It is also one of the world’s largest suppliers of generic APIs, amino acids and cell culture ingredients, and a top three global CMO for APIs and intermediates.
